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Cobimetinib- and vemurafenib-induced granulomatous dermatitis and erythema induratum: A case report.

Author: IafollaMarco Aj, McWhirterElaine, RamsayJennifer, WismerJudy

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

BRAF and MEK inhibitors together can improve survival for metastatic melanoma patients, but these drugs may cause skin problems like granulomatous dermatitis and erythema induratum.
Paper Details　
Original Abstract of the Article :
Metastatic melanoma is an aggressive malignancy. Survival can be increased with the combination of BRAF and MEK inhibition. BRAF inhibitor-induced cutaneous toxicities can be attenuated with MEK inhibition. Here, we describe the first reported case of a patient with metastatic melanoma who developed...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537058/

データ提供：米国国立医学図書館（NLM）

Cobimetinib and Vemurafenib: A Desert Storm of Skin Side Effects

Metastatic melanoma, a formidable foe, is like a relentless sandstorm, spreading across the body. This study examines the potential side effects of combination therapy with cobimetinib and vemurafenib, drugs used to combat this disease.

The researchers report a case of a patient who developed granulomatous dermatitis and erythema induratum, potentially associated with the combination therapy. This case highlights the importance of monitoring for potential skin side effects, much like navigating a desert requires vigilance for potential hazards.

Navigating Skin Side Effects: A Careful Trek

This case report underscores the importance of monitoring for potential skin side effects, like carefully navigating a desert landscape. By understanding the potential risks associated with combination therapy, clinicians can provide timely interventions and ensure the safety of patients battling metastatic melanoma.

Dr. Camel's Conclusion

Metastatic melanoma, like a relentless sandstorm, presents a challenging landscape for both patients and clinicians. This case report explores the potential skin side effects associated with cobimetinib and vemurafenib combination therapy. The researchers have highlighted the importance of vigilance in monitoring for these side effects, much like carefully navigating a desert landscape requires awareness of potential hazards. By understanding these potential risks, clinicians can provide timely interventions and ensure the safety of patients battling this formidable disease.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

31205706

DOI: Digital Object Identifier

PMC6537058

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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