Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature.

Author: AkçayMurat, YükselSerkan

Paper Details 
Original Abstract of the Article :
Isotretinoin is widely used in the treatment of acne vulgaris and other dermatological diseases. Numerous side effects have been reported in the literature. A myocardial bridge occurs when segments of the coronary artery create an intramyocardial tunnel. Atherosclerotic plaque formation frequently o...See full text at original site
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引用元:
https://doi.org/10.5543/tkda.2018.67055

データ提供:米国国立医学図書館(NLM)

Isotretinoin and Possible Kounis Syndrome: A Case of Cardiovascular Side Effects

Isotretinoin, a commonly prescribed medication for acne, has a vast landscape of potential side effects, just as a vast desert can hold a diverse array of hidden dangers. This case report delves into a possible link between isotretinoin and Kounis syndrome, a rare condition characterized by acute coronary syndromes triggered by allergic or hypersensitivity reactions. Imagine a delicate coronary artery bridge, a crucial passageway for blood flow, that becomes vulnerable to blockage. This case highlights the potential risk of coronary thrombosis, a dangerous blockage of the artery, in a patient with a myocardial bridge who was treated with isotretinoin. The researchers suggest that the patient's experience may be a case of Kounis syndrome, potentially linked to isotretinoin use.

Navigating the Risks of Isotretinoin

This case report raises a critical question: could isotretinoin be a contributing factor to Kounis syndrome? The authors meticulously review the existing literature on cardiovascular side effects associated with isotretinoin, providing valuable insights into the potential risks associated with this medication. While further research is needed to definitively establish a link between isotretinoin and Kounis syndrome, this case serves as a reminder of the importance of careful monitoring for cardiovascular complications in patients taking isotretinoin.

Staying Alert to Potential Risks

This case report underscores the importance of staying informed about the potential side effects of medications, even those commonly prescribed. It's crucial to have open communication with your healthcare provider about any concerns or changes in your health, especially if you are taking isotretinoin. While the benefits of isotretinoin in treating acne are undeniable, it's essential to be aware of the potential risks and to take necessary precautions.

Dr.Camel's Conclusion

While this case report is a reminder of the potential complexities of medication side effects, it also serves as a testament to the meticulous approach of researchers in investigating these issues. The authors' thorough review of the literature and meticulous analysis of the patient's case provide valuable insights into the potential risks associated with isotretinoin. This research encourages us to remain vigilant in our pursuit of safer and more effective treatment options, always keeping patient safety at the forefront.
Date :
  1. Date Completed 2019-12-30
  2. Date Revised 2019-12-30
Further Info :

Pubmed ID

31219450

DOI: Digital Object Identifier

10.5543/tkda.2018.67055

Related Literature

SNS
PICO Info
in preparation
Languages

English

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