Paper Details

  1. Home
  2. Paper Details

Safety of combined salivary gland and multilevel intramuscular onabotulinumtoxinA injections with and without ethanol in pediatric patients with cerebral palsy: A retrospective study.

Author: FrielKathleen, KimHeakyung, LevinJared, ShovalHannah

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Combining botulinum toxin type A (BTX-A) injections for sialorrhea with intramuscular BTX-A injections for spasticity in the same procedure was found to be safe and effective. The study, which included 27 patients with cerebral palsy, reported that less than 10% of patients in both groups (salivary gland injections only and combined injections) experienced adverse events. Both approaches were equally effective in achieving their goals, with over 75% of patients reporting a greater than 50% improvement in sialorrhea for at least 2 months.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the safety of combining salivary gland onabotulinumtoxinA (BTX-A) injections for sialorrhea with intramuscular BTX-A injections for spasticity in the same procedure. DESIGN: A retrospective cohort study in a tertiary hospital center. Patients selected were younger than 20 yea...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.3233/PRM-180552

データ提供：米国国立医学図書館（NLM）

A Safe Oasis in the Desert of Cerebral Palsy: Combining Salivary Gland and Multilevel Intramuscular OnabotulinumtoxinA Injections

Navigating the challenging desert of cerebral palsy (CP) treatment requires finding effective and safe approaches. This study, like a camel caravan seeking a safe passage, examines the safety and efficacy of combining salivary gland onabotulinumtoxinA (BTX-A) injections for sialorrhea with intramuscular BTX-A injections for spasticity in pediatric patients with CP. The researchers retrospectively analyzed the data of 52 patients who received their first salivary gland BTX-A injection. They found that combining salivary gland and multi-level intramuscular BTX-A injections, with or without alcohol, was safe and effective in treating both sialorrhea and spasticity simultaneously.

A Combined Approach for Cerebral Palsy Treatment: Safety and Efficacy

The study's findings suggest that combining salivary gland BTX-A injections with multilevel intramuscular BTX-A injections appears to be safe and effective, offering a single treatment approach for both sialorrhea and spasticity. This approach is particularly beneficial for pediatric patients with CP, simplifying treatment and improving outcomes.

Navigating the Desert of Cerebral Palsy Treatment

This research provides valuable insights into the ongoing quest for effective and safe treatment options for CP. The study's findings suggest that combining salivary gland and multilevel intramuscular BTX-A injections might be a safe and effective approach, offering a potential oasis in the desert of CP treatment.

Dr. Camel's Conclusion

This research unveils a potential oasis in the desert of cerebral palsy treatment. Combining salivary gland and multilevel intramuscular onabotulinumtoxinA injections appears to be safe and effective, offering a streamlined approach to address both sialorrhea and spasticity simultaneously. These findings provide valuable insights for navigating the complex challenges of CP treatment.

Date :
  1. Date Completed 2020-05-22
  2. Date Revised 2020-05-22
Further Info :

Pubmed ID

31227667

DOI: Digital Object Identifier

10.3233/PRM-180552

Related Literature

Article Analysis
・Effects of onabotulinumtoxina injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.