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Intraventricular Plus Intravenous Tigecycline for the Treatment of Daptomycin Nonsusceptible Vancomycin-Resistant Enterococci in an Infant with Ventriculoperitoneal Shunt Infection.

Author: DalgicNazan, ŞahinAyşe

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Ventriculoperitoneal (VP) shunt infections are a serious complication that occurs in 4%-17% of VP shunt patients. The most common cause is Staphylococcus epidermidis. While vancomycin-resistant Enterococcus (VRE) is a common nosocomial pathogen, it rarely causes central nervous system infections. Daptomycin is a powerful antibiotic used to treat VRE infections.
Paper Details　
Original Abstract of the Article :
Ventriculoperitoneal (VP) shunt infection, which is 1 of the most important complications of VP shunt is observed at a rate of 4%-17%. Staphylococcus epidermidis is the most common causative agent. Vancomycin-resistant Enterococcus (VRE) is an increasingly common nosocomial pathogen that rarely caus...See full text at original site
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引用元：
https://doi.org/10.1016/j.wneu.2019.07.045

データ提供：米国国立医学図書館（NLM）

Treatment of Daptomycin Nonsusceptible Vancomycin-Resistant Enterococci

In the battle against infectious diseases, the emergence of antibiotic-resistant bacteria is a formidable challenge. This case report describes the successful treatment of a ventriculoperitoneal (VP) shunt infection caused by daptomycin nonsusceptible vancomycin-resistant Enterococci (VRE) in an infant. The authors report the use of a novel combination therapy involving intraventricular and intravenous tigecycline. The study aimed to highlight the potential effectiveness of this treatment approach for challenging VRE infections, offering a beacon of hope in the face of antibiotic resistance.

Combination Therapy for Challenging Infections

This case report demonstrates the potential efficacy of a combination therapy involving intraventricular and intravenous tigecycline for treating VRE infections. The authors describe the successful treatment of a complex case, indicating that this approach may be a viable option for patients with challenging infections. Imagine a camel caravan facing a sandstorm. This combination therapy, like a well-equipped caravan, is prepared to withstand the toughest challenges, providing a strong defense against resistant bacteria.

Hope in the Face of Antibiotic Resistance

This case report offers hope in the ongoing battle against antibiotic resistance. The successful treatment of this infant highlights the importance of exploring novel treatment strategies and combinations to overcome this growing threat.

Dr.Camel's Conclusion

This case report serves as a reminder that innovation is crucial in the fight against antibiotic resistance. By combining our knowledge and exploring new treatment strategies, we can overcome even the most challenging infections. The success of this treatment approach offers a glimmer of hope for the future of infectious disease management.

Date :
  1. Date Completed 2020-01-17
  2. Date Revised 2020-01-17
Further Info :

Pubmed ID

31302272

DOI: Digital Object Identifier

10.1016/j.wneu.2019.07.045

Related Literature

Article Analysis
・Effects of daptomycin injection
SNS
PICO Info
in preparation
Languages

English

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