Paper Details

  1. Home
  2. Paper Details

A drug safety evaluation of abiraterone acetate in the treatment of prostate cancer.

Author: CastellanPietro, CastellucciRoberto, CindoloLuca, De NunzioCosimo, MarchioniMichele, PrimiceriGiulia, SchipsLuigi, TemaGiorgia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This literature review examines the safety profile of abiraterone acetate (AA) in treating metastatic prostate cancer (mPCa). The review found that AA is generally well-tolerated and effective, particularly in asymptomatic or minimally symptomatic patients. However, known toxicities like mineralocorticoid- and corticosteroid-related adverse events and hepatotoxicity require careful monitoring.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>: To evaluate the safety profile characteristics of abiraterone acetate (AA) in the treatment of metastatic prostate cancer (mPCa). <b>Areas covered</b>: In this literature review the authors evaluate safety data from phase III trials investigating the combination of abiraterone ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/14740338.2019.1648428

データ提供：米国国立医学図書館（NLM）

Abiraterone Acetate: A Safe and Effective Treatment for Prostate Cancer

Prostate cancer is a significant health concern, and finding effective treatments is a top priority for researchers. This study, published in [journal name], focuses on the safety and efficacy of abiraterone acetate (AA), a medication used to treat metastatic prostate cancer (mPCa). This study delves into the vast and complex world of [oncology], offering valuable insights into the safety profile of this promising drug.

The authors meticulously reviewed data from phase III clinical trials that investigated the combination of abiraterone acetate and prednisone (AAP) in patients with mPCa. Their goal was to understand the drug's toxicity profile, its long-term effects, and its impact on quality of life.

The review revealed that abiraterone acetate appears to be a safe and effective treatment for mPCa, particularly in patients with mild or no symptoms. The authors highlight the importance of understanding the drug's known side effects, including mineralocorticoid and corticosteroid-related adverse events (AEs) and hepatotoxicity. They believe that this knowledge can help healthcare providers make informed decisions about treatment.

Understanding the Safety Profile: A Crucial Step

The study emphasizes the need to fully understand the safety profile of medications, particularly when dealing with complex diseases like prostate cancer. This research helps to illuminate the risks and benefits of abiraterone acetate, providing valuable information for physicians and patients.

Navigating Treatment Options: A Collaborative Journey

Understanding the potential side effects of medications is crucial for patients and their healthcare providers. Open communication and collaboration between doctors and patients can help to manage treatment risks and achieve optimal outcomes.

Dr. Camel's Conclusion

The study's findings are a beacon in the desert of prostate cancer research. By shedding light on the safety profile of abiraterone acetate, researchers pave the way for more informed and effective treatment options for patients. It's a reminder that knowledge is power, especially in the face of complex diseases.

Date :
  1. Date Completed 2019-09-04
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

31353982

DOI: Digital Object Identifier

10.1080/14740338.2019.1648428

Related Literature

Article Analysis
・Effective treatment of drug safety
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.