Efficacy and Safety of Combination Pharmacotherapy for Patients with Overactive Bladder: A Rapid Evidence Assessment.

Author: ChappleChristopher, GratzkeChristian, MaanenRob van, MuellerElizabeth R, RobinsonDudley, RollandCatherine, SiddiquiEmad, StaskinDavid, StoelzelMatthias

Paper Details 
Original Abstract of the Article :
CONTEXT: Oral pharmacotherapy consisting of antimuscarinics, β3-adrenoreceptor agonists, or combinations of these agents forms the mainstay of overactive bladder (OAB) management. OBJECTIVE: To evaluate the efficacy and safety of combination therapy in patients with OAB. EVIDENCE ACQUISITION: A li...See full text at original site
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引用元:
https://doi.org/10.1016/j.eururo.2019.07.010

データ提供:米国国立医学図書館(NLM)

Overactive Bladder: A Team Effort for Relief

Overactive bladder (OAB) is a common condition that affects many individuals. This research explores the effectiveness and safety of combination pharmacotherapy, a team approach to treating OAB. The authors reviewed studies that investigated the efficacy of combining different medications, such as antimuscarinics and β3-adrenoreceptor agonists, to manage OAB.

They analyzed data from clinical trials that compared combination therapy with monotherapy. The results showed that combining mirabegron with solifenacin was effective in reducing symptoms and improving quality of life in patients with OAB. Furthermore, the combination therapy was well tolerated, with side effects similar to those observed with individual medications.

The Benefits of a Combined Approach

This research suggests that a combined approach to treating OAB can be effective and well-tolerated. The findings highlight the potential benefits of combining medications to optimize treatment outcomes. The study encourages healthcare professionals to consider combination therapy as a viable option for patients with OAB.

Living with OAB

OAB can be a distressing condition, but effective treatment options exist. The findings of this research provide valuable insights into the potential of combination pharmacotherapy to manage OAB symptoms. It is important to consult with a healthcare professional to discuss your individual circumstances and the most appropriate treatment plan for you.

Dr. Camel's Conclusion

This research is like a caravan traversing the desert, bringing together different medications to create a more effective and well-tolerated treatment for OAB. It suggests that a combined approach can be a more effective solution than individual drugs. The findings offer hope for individuals with OAB and encourage a collaborative approach to managing this condition.

Date :
  1. Date Completed 2020-12-17
  2. Date Revised 2020-12-17
Further Info :

Pubmed ID

31416636

DOI: Digital Object Identifier

10.1016/j.eururo.2019.07.010

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