Sarecycline: a narrow spectrum tetracycline for the treatment of moderate-to-severe acne vulgaris.

Author: CharlesJean Elizze M, MooreAngela Yen, MooreStephen

Paper Details 
Original Abstract of the Article :
Sarecycline is a novel, narrow-spectrum, once-daily tetracycline-derived oral antibiotic that is FDA-approved in the US to be taken with or without food for moderate-to-severe acne vulgaris for ages 9 years of age and older. Sarecycline possesses anti-inflammatory properties and potent activity...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802708/

データ提供:米国国立医学図書館(NLM)

A Narrow Focus: Sarecycline for Moderate-to-Severe Acne

In the realm of dermatology, acne is a common concern that affects many individuals. This research delves into the use of sarecycline, a novel, narrow-spectrum tetracycline-derived antibiotic, for the treatment of moderate-to-severe acne vulgaris. This once-daily oral antibiotic has received FDA approval for its effectiveness in managing acne, even in challenging areas like the chest and back. Sarecycline exhibits potent activity against Gram-positive bacteria, including Cutibacterium acnes, while displaying minimal activity against enteric Gram-negative bacteria. The study demonstrates significant reduction in inflammatory lesions after 12 weeks of treatment, with noticeable improvements seen as early as week 3. While sarecycline shows promising results, it's important to note potential side effects like nausea and vaginal candidiasis, though these were reported at relatively low rates.

Sarecycline's Targeted Approach: A Promise for Acne Treatment

This research sheds light on sarecycline's potential as a targeted and effective treatment for moderate-to-severe acne. Its narrow-spectrum action, focusing primarily on acne-causing bacteria, reduces the risk of disrupting beneficial gut flora. The study's findings, demonstrating significant reduction in inflammatory lesions and early improvements, highlight sarecycline's promise in this area. While some side effects are reported, their relatively low frequency suggests that sarecycline could be a valuable addition to the acne treatment arsenal.

Managing Acne: Taking a Holistic Approach

While sarecycline offers a promising solution for acne, it's important to approach acne management holistically. Factors like diet, stress, and skincare routines play a crucial role in achieving clear skin. Consulting a dermatologist is crucial for personalized advice and treatment plans, as each individual's skin and needs are unique. Remember, maintaining a healthy lifestyle can significantly contribute to achieving clear skin, and sarecycline can be a valuable tool in this journey.

Dr. Camel's Conclusion

This research, like a desert flower blooming in a harsh environment, offers hope for individuals seeking relief from acne. Sarecycline, with its targeted action against acne-causing bacteria, presents a promising new avenue for treatment. However, remember, as with any medical treatment, it's essential to consult with a healthcare professional for personalized advice and a comprehensive approach to managing acne.
Date :
  1. Date Completed 2020-05-07
  2. Date Revised 2020-05-07
Further Info :

Pubmed ID

31475868

DOI: Digital Object Identifier

PMC6802708

Related Literature

SNS
PICO Info
in preparation
Languages

English

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