Dupuytren, Ledderhose, and Peyronie Diseases After Primidone Use For Essential Tremor.

Author: NassifDaniel, SpitzMariana, VasconcellosLuiz Felipe R

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Dupuytren, Ledderhose, and Peyronie diseases are chronic fibrotic conditions related to progressive fibrosis of the palmar fascia, plantar fascia, and tunica albuginea, respectively. These conditions have been associated with antiepileptic drug use, mainly phenobarbital and primidone. ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/31478998

データ提供:米国国立医学図書館(NLM)

Primidone: A Potential Desert Storm for Connective Tissues

The world of pharmaceuticals is a complex desert, where medications can sometimes have unexpected side effects. This case report explores a potential link between primidone, a medication used to treat essential tremor, and the development of Dupuytren's, Ledderhose's, and Peyronie's diseases, rare fibrotic conditions affecting the hands, feet, and penis, respectively. The researchers describe a patient who developed all three conditions after long-term primidone use.

A Cautionary Tale: The Desert Storm of Side Effects

This case report serves as a cautionary tale, highlighting the potential for primidone to trigger a desert storm of connective tissue disorders. While the link between primidone and these conditions remains to be fully established, this case report suggests that physicians should be aware of this potential side effect and monitor patients closely for any signs of these disorders.

Navigating the Desert of Medication Side Effects

This case report reminds us that the desert of pharmaceutical side effects can be unpredictable and sometimes even devastating. It highlights the importance of careful monitoring and open communication between patients and their healthcare providers. By being aware of potential side effects and recognizing early warning signs, we can better navigate the desert of medication side effects and protect our health.

Dr.Camel's Conclusion

This case report, like a mirage in the desert, reminds us that even seemingly safe medications can have unexpected consequences. The potential link between primidone and connective tissue disorders highlights the importance of vigilance and open communication between patients and their healthcare providers. By being aware of potential side effects, we can navigate the desert of pharmaceutical side effects with greater caution and care.

Date :
  1. Date Completed 2020-02-17
  2. Date Revised 2020-02-17
Further Info :

Pubmed ID

31478998

DOI: Digital Object Identifier

00127893-201909000-00003

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.