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Systematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw.

Author: AbdelsamieSamer, CampbellConor B, FieldingAllen F, Heifetz-LiJiean Joseph, MulliganJoseph P, RothStephanie

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review evaluates the clinical usefulness of pentoxifylline and tocopherol in treating medication-related osteonecrosis of the jaw (MRONJ).
Paper Details　
Original Abstract of the Article :
Medication-related osteonecrosis of the jaw (MRONJ) is a pathologic process resulting in progressive destruction of the jaws. There are no established guidelines for the medical management of MRONJ. Interest in pentoxifylline and tocopherol is growing because these agents have been shown to be effec...See full text at original site
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引用元：
https://doi.org/10.1016/j.oooo.2019.08.004

データ提供：米国国立医学図書館（NLM）

Systematic Review of the Use of Pentoxifylline and Tocopherol for the Treatment of Medication-Related Osteonecrosis of the Jaw

This study delves into the intricate world of dental medicine, specifically examining the management of medication-related osteonecrosis of the jaw (MRONJ), a debilitating condition that causes progressive bone loss in the jaw. The researchers conducted a comprehensive review to evaluate the clinical usefulness of pentoxifylline and tocopherol, two agents that have shown promise in treating osteoradionecrosis of the jaw, in managing MRONJ.

Exploring Potential Therapies for MRONJ

The study suggests that pentoxifylline and tocopherol could potentially be effective in treating MRONJ, offering a glimmer of hope for individuals struggling with this challenging condition.

Maintaining Oral Health

The study emphasizes the importance of exploring potential treatments for MRONJ to improve the oral health and overall well-being of individuals affected by this condition.

Dr. Camel's Conclusion

This research, like a skilled dentist carefully examining a patient's jaw, meticulously explores potential therapies for MRONJ. It highlights the need for further investigation into these promising agents to offer a more effective treatment approach.
Date :
  1. Date Completed 2020-03-02
  2. Date Revised 2020-03-02
Further Info :

Pubmed ID

31488389

DOI: Digital Object Identifier

10.1016/j.oooo.2019.08.004

Related Literature

Article Analysis
・Effective treatment of osteonecrosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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