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Gingival Ischemia and Petechiae in a Patient Medicated With PCSK9 Inhibitor for Hypercholesterolemia: An Adverse Drug Event?
Author: ThermosGrigoris, TosiosKonstantinos I
Original Abstract of the Article :
Monoclonal antibodies against proprotein-convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a newly-introduced therapeutic approach against hypercholesterolemia. Clinical trials have reported few adverse effects of PCSK9 inhibitors and there are no reports of oral adverse effects. We present ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/cap.10043
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of Unexpected Side Effects
This case report explores a potential adverse drug event associated with the use of PCSK9 inhibitors, a new class of drugs used to treat hypercholesterolemia. The authors, like skilled detectives investigating a medical mystery, present a case of a patient who experienced gingival discomfort, ischemia, and petechiae after receiving alirocumab, a PCSK9 inhibitor. This case highlights the importance of careful monitoring and understanding the potential side effects of new medications.Unveiling the Hidden Dunes
This case report, like a discovery of a hidden oasis in the desert, reveals the potential for unexpected side effects with novel medications. It serves as a reminder that even with extensive clinical trials, new drugs can sometimes have unforeseen consequences.A Call for Vigilance
This case report underscores the importance of vigilant monitoring for potential side effects, particularly when using new medications. Like a desert traveler who must be aware of the changing terrain, healthcare providers must be alert to any signs of adverse reactions. This case also highlights the need for ongoing research to fully understand the potential risks and benefits of novel medications.Dr. Camel's Conclusion
This case report reminds us that the desert of drug development can be full of hidden dunes and unexpected challenges. It emphasizes the importance of careful monitoring and vigilance in the use of new medications, reminding us that even the most promising therapies can sometimes have unforeseen consequences.Date :
- Date Completed 2019-12-09
- Date Revised 2021-12-04
Further Info :
Related Literature
SNS
PICO Info
in preparation
Languages
English
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