Hemodynamic effects of felodipine in congestive heart failure.

Author: BinettiG, BranziA, FerrettiR M, GiovanelliN, MagnaniB, NegroniS, PancaldiS, SpecchiaS

Paper Details 
Original Abstract of the Article :
The hemodynamic effects of increasing dosages of felodipine, a new calcium antagonist with selective vasodilator properties, were studied in 13 patients with chronic cardiac failure. A Swan-Ganz thermodilution catheter was positioned in the pulmonary artery and hemodynamic parameters were monitored ...See full text at original site
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引用元:
https://doi.org/10.1007/BF02125469

データ提供:米国国立医学図書館(NLM)

Felodipine: A Vasodilator's Impact on Heart Failure

The human heart is a powerful engine, tirelessly pumping blood throughout the body. This research delves into the desert of cardiovascular medicine, exploring the effects of felodipine, a calcium antagonist with selective vasodilator properties, on patients with congestive heart failure. The researchers investigated the hemodynamic effects of increasing dosages of felodipine in 13 patients with chronic cardiac failure, meticulously monitoring their hemodynamic parameters for five days. Their findings revealed that felodipine significantly reduced systemic vascular resistance and increased cardiac index without increasing heart rate. The study also observed a dose-response effect, with increasing doses of felodipine leading to greater hemodynamic improvements.

Felodipine: A Potential Ally in the Fight Against Heart Failure

These findings suggest that felodipine can improve cardiac function and reduce the burden of congestive heart failure. The drug's ability to dilate blood vessels, leading to reduced resistance and improved blood flow, could offer a valuable therapeutic approach for this challenging condition.

Navigating the Desert of Heart Failure

Heart failure is a serious condition, and this research provides valuable insights into the potential benefits of felodipine. It encourages further research into the use of calcium antagonists with selective vasodilator properties for the management of heart failure.

Dr.Camel's Conclusion

This study demonstrates the potential benefits of felodipine in treating congestive heart failure, highlighting its vasodilatory effects and ability to improve cardiac function. This research is a significant step towards exploring new therapeutic options for patients with heart failure.

Date :
  1. Date Completed 1991-03-26
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3154319

DOI: Digital Object Identifier

10.1007/BF02125469

Related Literature

SNS
PICO Info
in preparation
Languages

English

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