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Decision-Analytic Modeling for Time-Effectiveness of the Sequence of Induction Treatments for Moderate to Severe Plaque Psoriasis.

Author: DresslerCorinna, GaskinsMatthew, NastAlexander, ZidaneMiriam

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Treatment sequences starting with a biological agent, including IXE-INF-SEC (1.4 weeks per DLQI-MID), INF-IXE-SEC (2.05 weeks per DLQI-MID), SEC-IXE-ADA (2.1 weeks per DLQI-MID), and ADA-IXE-SEC (2.8 weeks per DLQI-MID) were more time-effective than frequently used treatment sequences for moderate to severe plaque psoriasis.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: Systemic psoriasis treatments vary in efficacy and cost but also in time until onset of action. Patients with no response to a first induction treatment are typically switched to another, and some patients require several treatments before they see an improvement. OBJECTIVE: To determin...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802251/

データ提供：米国国立医学図書館（NLM）

Finding the Right Path for Psoriasis Treatment

Psoriasis is a chronic skin condition, like a persistent desert wind, that can be challenging to treat. This study explores different treatment sequences for moderate to severe plaque psoriasis, analyzing their effectiveness and cost-effectiveness. By modeling various treatment pathways, the study aims to identify the most efficient and cost-effective approach, ultimately leading to improved patient outcomes and reduced healthcare burden.

Timing is Key: Effective Psoriasis Treatment

This study highlights the importance of considering the time to onset of action when choosing psoriasis treatment. The study found that treatment sequences starting with biological agents were more time-effective than traditional approaches, potentially leading to faster symptom relief and improved quality of life for patients.

Navigating the Psoriasis Treatment Desert

This research provides valuable insights for managing psoriasis, emphasizing the importance of considering both the time to onset of action and cost-effectiveness when choosing treatment regimens. By understanding these factors, healthcare providers can optimize patient care and ensure that they receive the most efficient and effective treatment for their individual needs.

Dr.Camel's Conclusion

This study emphasizes the need to consider the time it takes for treatment to become effective when managing psoriasis. By comparing various treatment sequences, the study provides a valuable tool for doctors and patients alike, helping to navigate the complex landscape of psoriasis treatment and find the most efficient path to symptom relief.
Date :
  1. Date Completed 2021-05-12
  2. Date Revised 2021-05-12
Further Info :

Pubmed ID

31617856

DOI: Digital Object Identifier

PMC6802251

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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