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A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve.
Author: HuLin, LiTaoming, MengFanqi, WangWeici, YeQianqian, YinTao, ZouLe
Original Abstract of the Article :
OBJECTIVES: The primary objective of this study was to establish a novel method to assess the effect of imipenem/cilastatin (IMP) on liver function laboratory indexes in Chinese underage inpatients (inpatients aged <18 year-old). METHODS: A retrospective study was conducted in 188 underage inpatien...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812810/
データ提供:米国国立医学図書館(NLM)
Assessing the Impact of Imipenem/Cilastatin on Liver Function in Underage Patients
The administration of medications to children, especially those under 18 years old, is a delicate process that demands careful consideration. This study delves into the potential impact of imipenem/cilastatin (IMP), a commonly used antibiotic, on liver function in underage inpatients. Using a novel method called mean-variance induced by drug (MVID), this research seeks to shed light on the nuances of this medication's effect on liver function in this vulnerable patient population.
Imipenem/Cilastatin: A Potential for Liver Function Changes in Underage Patients
The study reveals that IMP can potentially affect liver function in a significant portion of underage patients. This finding underscores the importance of monitoring liver function in these patients during IMP treatment. The MVID analysis suggests that IMP can lead to an increase in certain liver enzymes, similar to how a desert sandstorm can temporarily impact the delicate balance of a desert ecosystem. However, the researchers also find that liver-protecting drugs can mitigate these effects, offering a glimmer of hope for managing potential side effects.
Imipenem/Cilastatin: A Call for Careful Monitoring and Targeted Intervention
This research emphasizes the need for careful monitoring of liver function in underage patients receiving IMP. The study underscores the importance of early intervention with liver-protecting drugs to minimize potential adverse effects. This research is like a desert guide, providing essential information for navigating the complexities of pediatric antibiotic therapy, ensuring that the journey is as safe and effective as possible.
Dr.Camel's Conclusion
This study highlights the potential impact of imipenem/cilastatin on liver function in underage patients, emphasizing the importance of careful monitoring and timely intervention with liver-protecting drugs. By understanding the nuances of this medication's effects, healthcare providers can optimize treatment outcomes and ensure the well-being of their young patients.
Date :
- Date Completed 2020-03-23
- Date Revised 2020-03-23
Further Info :
Related Literature
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