Paper Details

  1. Home
  2. Paper Details

From mitochondria to healthy aging: The role of branched-chain amino acids treatment: MATeR a randomized study.

Author: BuondonnoIlaria, CarignanoGiulia, D'AmelioPatrizia, DuttoFrancesca, FerreriCinzia, IsaiaGiovanni C, MassaiaMassimiliano, NisoliEnzo, PiliFausto G, PorrinoPaola, RavettaClaudia, RigantiChiara, RuoccoChiara, SassiFrancesca

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This randomized trial found that branched-chain amino acid enriched mixture (BCAAem) supplementation was more effective than simple diet advice in improving cognitive performance, muscle mass, strength, and physical performance in elderly malnourished patients.
Paper Details　
Original Abstract of the Article :
RATIONALE: Malnutrition often affects elderly patients and significantly contributes to the reduction in healthy life expectancy, causing high morbidity and mortality. In particular, protein malnutrition is one of the determinants of frailty and sarcopenia in elderly people. METHODS: To investigate...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.clnu.2019.10.013

データ提供：米国国立医学図書館（NLM）

The Role of Branched-Chain Amino Acids in Healthy Aging

Aging is an inevitable process that can lead to a decline in physical and cognitive function. It's like a desert landscape that gradually becomes more barren and difficult to navigate. This study examines the potential benefits of branched-chain amino acid (BCAA) supplementation in elderly malnourished patients. The researchers conducted an open-label randomized trial to investigate the effects of a BCAA-enriched mixture on nutritional status, cognitive performance, muscle mass, strength, and mitochondrial function in elderly individuals.

BCAA Supplementation: A Potential Fountain of Youth?

The study found that BCAA supplementation was more effective than simple diet advice in improving cognitive performance, measured by the Mini-Mental State Examination (MMSE), and in increasing mitochondrial ATP production and electron flux. These findings suggest that BCAA supplementation may play a role in promoting healthy aging by supporting mitochondrial function and cognitive health.

Nourishing the Body and Mind Through BCAA Supplementation

This study highlights the potential of BCAA supplementation in supporting healthy aging. It's like finding a hidden oasis in the desert, offering nourishment and revitalization. While further research is needed to confirm these findings, BCAA supplementation may be a valuable tool in addressing age-related decline in physical and cognitive function.

Dr.Camel's Conclusion

This study suggests that BCAA supplementation may play a role in promoting healthy aging. It's like discovering a new source of water in the desert, helping to sustain life and vitality. While more research is needed, BCAA supplementation shows promise in supporting both physical and cognitive health in older adults.

Date :
  1. Date Completed 2021-08-16
  2. Date Revised 2021-08-16
Further Info :

Pubmed ID

31672329

DOI: Digital Object Identifier

10.1016/j.clnu.2019.10.013

Related Literature

Article Analysis
・Effective treatment of healthy aging
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.