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Adverse events related to abiraterone and enzalutamide treatment: analysis of the EudraVigilance database and meta-analysis of registrational phase III studies.
Author: BaldassarriValeria, BracardaSergio, De NunzioCosimo, IacovelliRoberto, LombardoRiccardo, NacchiaAntonio, SicaAngela, TemaGiorgia, TubaroAndrea, VoglinoOlivia
Original Abstract of the Article :
Data from clinical trials do not always provide adequate information to judge the impact of new treatments when used in a real-world setting. The aim of our study was to analyze adverse events (AEs) associated with enzalutamide (ENZ) and abiraterone (ABI) using real-life data from the EudraVigilance...See full text at original site
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引用元:
https://doi.org/10.1038/s41391-019-0182-x
データ提供:米国国立医学図書館(NLM)
Adverse Events of Abiraterone and Enzalutamide
The world of medicine is a vast and ever-evolving desert, filled with new treatments and challenges. This research examines the adverse events associated with two drugs, abiraterone and enzalutamide, used to treat prostate cancer. The authors analyzed data from the EudraVigilance database, a real-world source of information about drug safety, to identify common side effects of these drugs. Their study provides valuable insights into the potential risks associated with these treatments, guiding clinicians in making informed decisions about patient care.
Real-World Safety Data
The study found that abiraterone and enzalutamide were associated with a range of adverse events, some of which were serious. These included cardiovascular events, metabolic disorders, and liver toxicity. The study highlights the importance of carefully monitoring patients receiving these drugs for potential side effects and adjusting treatment strategies as needed. This research provides valuable information for clinicians, enabling them to make informed decisions about the use of these drugs in the context of individual patient needs and risk profiles.
Implications for Prostate Cancer Treatment and Drug Safety
The study's findings highlight the importance of ongoing monitoring and evaluation of drug safety in a real-world setting. This research provides valuable data for clinicians, enabling them to make informed decisions about the use of abiraterone and enzalutamide in treating prostate cancer. The study underscores the importance of carefully weighing the potential benefits and risks of these drugs, considering factors like patient health status and the severity of their disease. Like a camel traversing a desert, we must navigate the challenges of cancer treatment with caution and vigilance, ensuring the safety and well-being of our patients.
Dr.Camel's Conclusion
This research provides valuable insights into the real-world safety of abiraterone and enzalutamide. The study highlights the importance of carefully monitoring patients for potential side effects and making informed decisions about treatment strategies. As researchers, we must continue to explore the vast desert of medicine, seeking new oases of knowledge to improve patient safety and well-being.
Date :
- Date Completed 2021-03-08
- Date Revised 2021-12-04
Further Info :
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