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Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors: A Clinician's Guide.

Author: MacGregorGordon G, SimesBryce C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

SGLT2 inhibitors are an oral medication used to treat type 2 diabetes. These drugs work by blocking the reabsorption of glucose in the kidneys, leading to lower blood sugar levels. While effective, SGLT2 inhibitors can also cause side effects like genital tract infections, lower leg amputations, electrolyte disturbances, and bone fractures. However, they have shown promise in treating other conditions besides type 2 diabetes, including non-alcoholic fatty liver disease, obesity, and high blood pressure.
Paper Details　
Original Abstract of the Article :
This comprehensive review covers the historical background, physiology, application in type 2 diabetes, novel uses, cardiovascular benefits, side effects and contraindications of sodium-glucose cotransporter-2 (SGLT2) inhibitors. SGLT2 inhibitors are an insulin-independent class of oral antihypergly...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799898/

データ提供：米国国立医学図書館（NLM）

SGLT2 inhibitors: a beacon in the desert of diabetes management

Diabetes, a condition that affects millions worldwide, is a major public health concern. The search for effective and safe treatments continues, with new medications constantly emerging. This comprehensive review explores the role of SGLT2 inhibitors, a class of oral antihyperglycemic medications, in the management of type 2 diabetes. SGLT2 inhibitors work by blocking a protein involved in reabsorbing glucose back into the bloodstream, thus reducing blood sugar levels. This review delves into the historical background, mechanism of action, clinical applications, cardiovascular benefits, side effects, and novel uses of SGLT2 inhibitors.

SGLT2 inhibitors: a promising addition to type 2 diabetes management

The review highlights the effectiveness of SGLT2 inhibitors in lowering blood sugar levels, reducing cardiovascular risk, and promoting weight loss. However, it also emphasizes the importance of careful patient selection and monitoring due to potential side effects.

Living with diabetes: a desert journey with SGLT2 inhibitors

This review suggests that SGLT2 inhibitors could be a valuable tool for managing type 2 diabetes, but they are not a one-size-fits-all solution. It's crucial to discuss with your doctor whether these medications are appropriate for you and to understand their potential benefits and risks.

Dr.Camel's Conclusion

SGLT2 inhibitors represent a significant advancement in diabetes management. While they offer numerous benefits, it's essential to remember that every desert journey is unique. Consulting your doctor is crucial to ensure the best possible outcome for your individual needs.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

31686884

DOI: Digital Object Identifier

PMC6799898

SNS
PICO Info
in preparation
Languages

English

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