Mucoadhesive effect of Curcuma longa extract and curcumin decreases the ranitidine effect, but not bismuth subsalicylate on ethanol-induced ulcer model.

Author: Balderas-LópezJosé Luis, Bernad-BernadMaría Josefa, Medina-TorresLuis, NavarreteAndrés, Orona-OrtizAlejandra, Pineda-PeñaElizabeth A, Tavares CarvalhoJosé Carlos, Velázquez-MoyadoJosué A

Paper Details 
Original Abstract of the Article :
The study of pharmacological interactions between herbal remedies and conventional drugs is important because consuming traditional herbal remedies as supplements or alternative medicine is fairly common and their concomitant administration with prescribed drugs could either have a favorable or unfa...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851106/

データ提供:米国国立医学図書館(NLM)

Unmasking the Interaction Between Herbs and Conventional Drugs

The use of herbal remedies has become increasingly popular, often used alongside conventional medications. Imagine a desert landscape where a variety of plants grow, each with their own unique properties and potential interactions. This study explores the potential pharmacological interactions between turmeric extract and curcumin, two common herbal ingredients, and two widely used anti-ulcer drugs, ranitidine and bismuth subsalicylate. The authors investigated the effects of these combinations on ethanol-induced ulcers in rats, finding that turmeric extract and curcumin had a subadditive effect when combined with ranitidine, potentially reducing its effectiveness. However, the combination with bismuth subsalicylate showed an additive effect, suggesting that these two components could work together to reduce ulcers.

The Importance of Drug Interactions

This study highlights the importance of understanding potential interactions between herbal remedies and conventional medications. Just as a desert explorer needs to be aware of the potential dangers of different plants and animals, we need to be mindful of the potential interactions between the medications we take. This study reminds us that combining herbal remedies with conventional drugs can have unexpected consequences, potentially affecting their efficacy or safety. It emphasizes the importance of consulting healthcare professionals before taking any new herbal remedies, especially when combined with existing medications.

Navigating the World of Herbal Remedies

The study's findings encourage a cautious approach to using herbal remedies, especially when combined with conventional medications. Just as a desert traveler needs to choose their path carefully, we need to be mindful of the potential interactions between the substances we consume. This study underscores the importance of evidence-based medicine, encouraging the use of validated and well-researched herbal remedies, while also considering the potential for interactions with other medications.

Dr. Camel's Conclusion

Like a camel who has learned to identify the nourishing plants and avoid the poisonous ones in the desert, we must be mindful of the potential interactions between different substances, both natural and synthetic. This study highlights the need for careful consideration when combining herbal remedies with conventional medications, reminding us that a little bit of knowledge can go a long way in ensuring our safety and well-being.

Date :
  1. Date Completed 2020-11-10
  2. Date Revised 2021-01-10
Further Info :

Pubmed ID

31719599

DOI: Digital Object Identifier

PMC6851106

Related Literature

SNS
PICO Info
in preparation
Languages

English

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