Bacillus Calmette-Guérin immunotherapy for bladder cancer: a review of immunological aspects, clinical effects and BCG infections.

Author: GolettiDelia, JoensenUlla Nordström, JohansenIsik Somuncu, LarsenEmilie Stavnsbjerg, PoulsenAlicia Martin

Paper Details 
Original Abstract of the Article :
Bacillus Calmette-Guérin (BCG) immunotherapy for bladder cancer has been used since 1976 when the first evidence of its ability to lower recurrence and progression rates was published. Today, BCG immunotherapy is the choice of care for high-grade non-muscle invasive bladder cancer (NMIBC) after tran...See full text at original site
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引用元:
https://doi.org/10.1111/apm.13011

データ提供:米国国立医学図書館(NLM)

BCG Immunotherapy for Bladder Cancer: A Comprehensive Review

Bladder cancer is a significant health concern, and BCG immunotherapy has emerged as a cornerstone of treatment for high-grade non-muscle invasive bladder cancer. This review provides a comprehensive overview of BCG immunotherapy, delving into its history, mechanisms of action, clinical efficacy, and potential side effects. The authors discuss the complex immune responses elicited by BCG, highlighting the intricate interplay of various immune cells and mediators in achieving tumor eradication. The review also explores the potential role of the urinary microbiome in influencing treatment outcomes and addresses the management of BCG-related infections.

BCG Immunotherapy: A Multifaceted Approach

The review highlights the multifaceted nature of BCG immunotherapy, revealing its complex mechanisms of action. The authors delve into the intricate interactions between BCG and the immune system, shedding light on the intricate pathways involved in tumor control. This comprehensive review provides a valuable resource for clinicians and researchers seeking to understand the nuances of BCG immunotherapy.

Navigating the Terrain of Bladder Cancer Treatment

This review provides a roadmap for navigating the complex terrain of bladder cancer treatment. It offers valuable insights into the efficacy, mechanisms of action, and potential complications of BCG immunotherapy. The review emphasizes the need for careful patient monitoring and a comprehensive understanding of BCG's effects to ensure optimal outcomes. Like a desert traveler armed with a guidebook, clinicians can utilize this knowledge to navigate the complexities of bladder cancer treatment.

Dr. Camel's Conclusion

This review delves into the intricate world of BCG immunotherapy, a treatment strategy that leverages the power of the immune system to combat bladder cancer. It's like navigating a vast desert, uncovering the secrets of a complex ecosystem and utilizing its resources to achieve success.

Date :
  1. Date Completed 2020-05-08
  2. Date Revised 2020-05-08
Further Info :

Pubmed ID

31755155

DOI: Digital Object Identifier

10.1111/apm.13011

SNS
PICO Info
in preparation
Languages

English

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