Therapeutic Opportunities with Pharmacological Inhibition of CD38 with Isatuximab.

Author: AbbadessaGiovanni, AndersonKenneth C, CampanaFrank, ChironMarielle, CorzoKathryn, LeeHelen, MartinThomas G, MengRobin, RakAlexey, SolankiMalini, VeldeHelgi van de, WiederschainDmitri, ZhuChen

Paper Details 
Original Abstract of the Article :
CD38 is a transmembrane glycoprotein with ectoenzymatic activity involved in regulation of migration, signal transduction, and receptor-mediated adhesion. CD38 is highly expressed on various malignant cells, including multiple myeloma (MM), and at relatively low levels in other tissues, making it a ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953105/

データ提供:米国国立医学図書館(NLM)

Isatuximab: A New Frontier in Multiple Myeloma Treatment

This study ventures into the complex world of cancer treatment, focusing on multiple myeloma, a type of blood cancer. They investigate the potential of isatuximab, a monoclonal antibody targeting CD38, a protein found on myeloma cells, as a therapeutic agent. The study highlights the promising results of isatuximab in treating relapsed/refractory multiple myeloma, suggesting its potential as a new treatment option for this challenging disease. It's like finding a hidden oasis of hope in the vast desert of cancer treatment options!

Isatuximab: A Targeted Approach to Multiple Myeloma

This research reveals the potential of isatuximab as a targeted therapy for multiple myeloma. The study found that isatuximab effectively targets CD38, a protein found on myeloma cells, leading to significant improvements in treatment outcomes. It's like finding a precise weapon in the arsenal against this challenging disease, offering a more targeted and effective approach to treatment.

A New Era of Multiple Myeloma Treatment: Harnessing the Power of Monoclonal Antibodies

From a health perspective, this study suggests a new era of multiple myeloma treatment. Isatuximab offers a promising new approach to targeting and destroying myeloma cells, providing hope for patients who have previously faced limited treatment options. It's like finding a new source of water in a parched desert, offering a lifeline to those in need. This research represents a significant step forward in the ongoing battle against cancer, paving the way for a healthier future for those affected by multiple myeloma.

Dr.Camel's Conclusion

This research showcases the promise of isatuximab as a targeted therapy for multiple myeloma. It's a testament to the ongoing advancements in cancer treatment, offering hope and relief to those battling this challenging disease. Just as a camel traverses the desert with resilience, we can approach cancer treatment with confidence and a commitment to innovation. Isatuximab represents a valuable tool in our arsenal, helping us to navigate the complexities of this disease with strength and determination.

Date :
  1. Date Completed 2020-07-24
  2. Date Revised 2023-11-04
Further Info :

Pubmed ID

31779273

DOI: Digital Object Identifier

PMC6953105

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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