Paper Details

  1. Home
  2. Paper Details

Comparison of the Effects of Propofol and Sevoflurane on QT Interval in Pediatrics Undergoing Cochlear Implantation: A Randomized Clinical Trial Study.

Author: AhmadiAslan, AlimianMahzad, AshrafHaleh, HassaniValiollah, KoleiniZahra Sadat, MohebiElham, MohseniMasood, MovaseghiGholamreza, PourkandShayesteh, SafaeianReza

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Propofol may be safer than inhalational sevoflurane for induction of anesthesia in children with sensorineural hearing loss whose pre-induction QTc is not longer than 500 ms. In a double-blind randomized clinical trial, sevoflurane caused a significant post-induction difference in QTc values compared to propofol.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Children with sensorineural hearing loss are at risk of cardiac electrophysiologic abnormalities. Inhalational Sevoflurane induction in these children can cause QT prolongation. OBJECTIVES: In order to evaluate the safety of inhalational induction of anesthesia with sevoflurane in child...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885132/

データ提供：米国国立医学図書館（NLM）

Propofol vs. Sevoflurane: A Comparative Study for Anesthesia in Cochlear Implant Surgery

Children with sensorineural hearing loss undergoing cochlear implantation often face cardiac electrophysiologic abnormalities. This randomized clinical trial aimed to compare the effects of propofol and sevoflurane on the QT interval, a measure of heart rhythm, in children undergoing cochlear implantation. The researchers randomly assigned 61 children to receive anesthesia with either propofol or sevoflurane. The study revealed that propofol resulted in a shorter QT interval compared to sevoflurane, suggesting that propofol might be a safer option for anesthesia induction in this patient population.

Propofol: A Safer Choice for Anesthesia in Cochlear Implant Surgery?

The study's findings suggest that propofol may be a safer anesthetic option for children undergoing cochlear implantation, potentially reducing the risk of QT prolongation. This research highlights the importance of careful consideration of anesthetic agents based on individual patient factors, particularly in children with pre-existing cardiac conditions.

Navigating the Desert of Cochlear Implant Surgery

The desert of cochlear implant surgery is a challenging landscape, requiring delicate navigation to ensure optimal outcomes. This study, like a compass guiding us through the terrain, provides valuable insights into choosing the most appropriate anesthetic agent, potentially minimizing risks and maximizing patient safety.

Dr.Camel's Conclusion

This research emphasizes the significance of careful anesthetic selection, particularly for children undergoing cochlear implantation. The study's findings suggest that propofol may be a safer option than sevoflurane, potentially reducing the risk of QT prolongation. This research underscores the importance of tailoring anesthesia protocols to individual patient needs to ensure the best possible outcomes during this intricate surgical procedure.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-11
Further Info :

Pubmed ID

31803586

DOI: Digital Object Identifier

PMC6885132

Related Literature

Article Analysis
・Effective treatment of pediatrics
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.