Targeted therapy in pulmonary veno-occlusive disease: time for a rethink?

Author: JinQi, LiuZhihong, LuoQin, XiongChangming, YanLu, YuXue, ZhangYi, ZhaoQing, ZhaoZhihui

Paper Details 
Original Abstract of the Article :
Pulmonary veno-occlusive disease (PVOD) is a rare condition with poor prognosis, and lung transplantation is recommended as the only curative therapy. The role of pulmonary arterial hypertension targeted therapy in PVOD remains controversial, and long-term effects of targeted therapy have been rarel...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924010/

データ提供:米国国立医学図書館(NLM)

Rethinking Targeted Therapy in Pulmonary Veno-Occlusive Disease

The realm of pulmonary diseases is a vast and challenging desert, where patients often face debilitating and life-threatening conditions. This

study delves into the world of

respiratory medicine, specifically focusing on pulmonary veno-occlusive disease (PVOD), a rare and often fatal condition characterized by blockage of the small veins in the lungs. The researchers explored the role of targeted therapy, a treatment approach aimed at specific molecular targets involved in the disease, in patients with PVOD. They sought to evaluate the long-term efficacy and safety of these therapies and assess their potential as a treatment option for this challenging condition.

Navigating the Shifting Sands of PVOD Treatment

The study provides a retrospective analysis of targeted therapy in patients with PVOD, examining the long-term effects of these therapies. While lung transplantation remains the only curative treatment for PVOD, the researchers explored the potential of targeted therapy to manage symptoms and improve quality of life. They highlighted the need for further research to better understand the long-term effects of these therapies and determine their optimal role in the management of PVOD.

The Importance of Personalized Treatment Approaches

This study emphasizes the importance of personalized treatment approaches for patients with PVOD. The researchers acknowledge the limitations of current data and the need for more comprehensive research to guide treatment decisions. Healthcare professionals should carefully consider the individual characteristics of each patient, including the severity of their condition and their tolerance for different medications, when developing treatment plans.

Dr. Camel's Conclusion

The desert of pulmonary diseases can be a challenging and unforgiving place, and PVOD is a particularly daunting condition. This study provides valuable insights into the potential role of targeted therapy in managing this disease, highlighting the need for further research to optimize treatment strategies. By carefully considering individual needs and pursuing ongoing research, we can work towards finding more effective and personalized treatments for patients with PVOD.

Date :
  1. Date Completed 2020-06-01
  2. Date Revised 2020-06-01
Further Info :

Pubmed ID

31856792

DOI: Digital Object Identifier

PMC6924010

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Languages

English

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