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Dapagliflozin-induced Late-onset Euglycemic Diabetic Ketoacidosis.
Author: HamidMohsin, IqbalIqra, KainatAleesha, KhanMuhammad Atique Alam, TariqShafaq
Original Abstract of the Article :
Sodium-glucose co-transporter-2 (SGLT2) inhibitors are a class of oral hypoglycemics that improve glycemic control by increasing the urinary excretion of glucose. They gained widespread popularity because they not only showed improved glycemic control but also had a favorable effect on weight loss, ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897349/
データ提供:米国国立医学図書館(NLM)
Dapagliflozin: A Powerful Drug with a Rare but Serious Side Effect
The world of [diabetes management] has seen significant advancements in recent years, with new drug classes emerging to improve glycemic control. This research delves into the rare but potentially serious side effect of euglycemic diabetic ketoacidosis (eDKA) associated with the use of dapagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor.
The authors present a case report of a patient who developed late-onset eDKA after stopping dapagliflozin. This case is particularly intriguing because the patient had already stopped taking the medication two weeks before experiencing the symptoms. The authors highlight the challenges in diagnosing eDKA, particularly due to near-normal glucose levels.
A Rare But Serious Side Effect
The research underscores the importance of recognizing the potential for eDKA, even when patients have stopped taking dapagliflozin. Healthcare providers need to be aware of the delayed onset of this side effect and remain vigilant in monitoring patients who have been prescribed SGLT2 inhibitors.
Ensuring Patient Safety
This research highlights the importance of careful patient selection and monitoring when prescribing SGLT2 inhibitors. Understanding the potential for eDKA and recognizing its symptoms are critical for ensuring patient safety.
Dr.Camel's Conclusion
The journey of managing diabetes requires a delicate balance between treatment benefits and potential risks. This research serves as a reminder that even seemingly safe drugs can have rare but serious side effects. Like a wise camel navigating the shifting sands of the desert, healthcare providers must remain vigilant in monitoring their patients and adjusting treatment plans accordingly.
Date :
- Date Completed n.d.
- Date Revised 2020-09-28
Further Info :
Related Literature
English
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