Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study.

Author: AndradeBruno B, AraujoNelia C N, ArriagaMaría B, CaldasSimone C C, NettoEduardo M, TorresNinfa M C

Paper Details 
Original Abstract of the Article :
BACKGROUND: The Ministry of Health in Brazil included ethambutol in the intensive phase of sensible tuberculosis (TB) treatment in March 2010, due to the increasing drug resistance, and implemented the fixed dose combination in the TB treatment guidelines. METHODS: A retrospective cohort study was ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932797/

データ提供:米国国立医学図書館(NLM)

Tuberculosis Treatment Regimens: Exploring the Impact of Ethambutol

The field of [Infectious Disease] is dedicated to combating [Tuberculosis], a serious infectious disease that continues to impact global health. This study investigates the impact of a change in [Antitubercular Regimen] from three to four drugs on [Cure Rates] and [Adverse Drug Reactions]. The authors analyzed data from [Tuberculosis Patients] in Brazil, comparing the outcomes of those receiving the [RHEZ] regimen to those receiving the [RHZ] regimen. Their findings reveal that the [RHEZ] regimen was associated with a higher frequency of [Adverse Drug Reactions] compared to the [RHZ] regimen, particularly in patients over 30 years old. However, the study found no significant difference in [Cure Rates] between the two regimens. This research provides valuable insights into the potential risks and benefits of different [Antitubercular Regimens] for [Tuberculosis Patients].

Balancing Treatment Effectiveness and Side Effects in Tuberculosis

This research highlights the complex considerations involved in managing [Tuberculosis]. While the [RHEZ] regimen appears to be effective in achieving [Cure Rates], it also carries a higher risk of [Adverse Drug Reactions]. This study provides a valuable framework for understanding the trade-offs between [Treatment Efficacy] and [Drug Safety] in managing this challenging disease.

Navigating Tuberculosis Treatment: A Collaborative Approach

It's crucial to work closely with your healthcare provider to determine the best [Antitubercular Regimen] for your individual needs. Factors like [Age] and [Preexisting Conditions] can influence the appropriate treatment approach. Remember, [Tuberculosis] is a serious disease, and it's essential to seek prompt medical attention if you experience any symptoms.

Dr. Camel's Conclusion

The world of [Tuberculosis] treatment is a vast desert, with multiple pathways to navigate. This study explores the impact of different [Antitubercular Regimens], highlighting the importance of careful consideration of both [Treatment Efficacy] and [Drug Safety]. Like a camel seeking the best path through the desert, it's essential to work closely with your healthcare provider to determine the most effective and safe treatment option for you. Remember, knowledge empowers you to make informed decisions about your health.

Date :
  1. Date Completed 2020-04-02
  2. Date Revised 2023-11-12
Further Info :

Pubmed ID

31877199

DOI: Digital Object Identifier

PMC6932797

Related Literature

SNS
PICO Info
in preparation
Languages

English

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