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Topical minoxidil: cardiac effects in bald man.

Author: LeenenF H, SmithD L, UngerW P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Topical minoxidil, applied for 6 months, did not affect blood pressure but increased heart rate in healthy subjects. Although the treatment caused some cardiovascular effects, including increased heart size and output, short-term use is likely safe. However, further research is needed to evaluate long-term safety in patients with coronary artery disease and healthy subjects.
Paper Details　
Original Abstract of the Article :
Systemic cardiovascular effects during chronic treatment with topical minoxidil vs placebo were evaluated using a double-blind, randomized design for two parallel groups (n = 20 for minoxidil, n = 15 for placebo). During 6 months of follow-up, blood pressure did not change, whereas minoxidil increas...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1365-2125.1988.tb03410.x

データ提供：米国国立医学図書館（NLM）

Topical Minoxidil and its Cardiovascular Impact

The quest for solutions to hair loss is a journey many embark on, often with hopes of restoring a youthful appearance. This research explores the potential cardiovascular effects of topical minoxidil, a common treatment for hair loss. It's like examining the hidden currents in a vast ocean, seeking to understand the subtle ways in which this medication might affect our bodies.

This double-blind, randomized study compared the effects of topical minoxidil to a placebo over six months. The researchers carefully measured various cardiovascular parameters, akin to charting the course of a ship across a stormy sea, seeking to understand the potential risks and benefits of this treatment.

While the study found that short-term use of topical minoxidil is likely safe for healthy individuals, it also raised concerns about potential long-term effects, especially for individuals with coronary artery disease. It's a reminder that even seemingly straightforward solutions can have unexpected consequences, just as a desert mirage can deceive weary travelers.

Balancing Benefits and Risks

The study highlighted the importance of weighing the potential benefits of topical minoxidil against its potential risks. It's a delicate balance, like navigating a narrow canyon where the risks of falling are high, but the reward of reaching the other side is great.

Considering Your Cardiovascular Health

If you are considering topical minoxidil for hair loss, it's essential to consult with your healthcare provider to discuss your individual health risks and potential side effects. It's like consulting a seasoned desert guide before embarking on a perilous journey; they can help you make informed decisions and avoid unnecessary dangers.

Dr.Camel's Conclusion

This research underscores the importance of understanding the full spectrum of potential effects, even for seemingly simple treatments. It's a reminder that as we continue to explore the vast desert of medical knowledge, we must always remain vigilant and consider the potential consequences of our actions.

Date :
  1. Date Completed 1988-12-28
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3191000

DOI: Digital Object Identifier

10.1111/j.1365-2125.1988.tb03410.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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