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A systematical comparison of anti-angiogenesis and anti-cancer efficacy of ramucirumab, apatinib, regorafenib and cabozantinib in zebrafish model.

Author: FanRuo-Yue, HeMing-Fang, HeZhi-Heng, LiChong-Yong, ShenLi-Zong, WeiPin, WuJia-Qi, ZhangShi-Ru

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study systemically compared the anti-angiogenesis, anti-cancer efficacy, and safety of four anti-angiogenic drugs (ramucirumab, apatinib, regorafenib, and cabozantinib) for the treatment of gastric cancer.
Paper Details　
Original Abstract of the Article :
Gastric cancer (GC) is one of the most common malignant tumors in the world. Anti-angiogenic therapy is a useful strategy for the treatment of advanced GC. This study was aimed to systemically compare the anti-angiogenesis, anti-cancer efficacy, as well as the safety of four known anti-angiogenic dr...See full text at original site
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引用元：
https://doi.org/10.1016/j.lfs.2020.117402

データ提供：米国国立医学図書館（NLM）

Anti-angiogenesis: A New Weapon in the Fight Against Gastric Cancer

This study provides a comparative analysis of four anti-angiogenic drugs (ramucirumab, apatinib, regorafenib, and cabozantinib) in a zebrafish model of gastric cancer. The research aims to identify the most effective anti-angiogenesis and anti-cancer agents among these drugs, considering their efficacy, safety, and potential impact on tumor growth and angiogenesis.

A Desert Oasis of Hope: Fighting Gastric Cancer

This research, like a desert oasis, offers a promising approach to fighting gastric cancer through targeted therapies. The study's comparative analysis of anti-angiogenic drugs provides valuable insights for developing effective treatment strategies and improving patient outcomes.

A Path Through the Sands: Targeting Angiogenesis

This study navigates the intricate mechanisms of angiogenesis, a process essential for tumor growth. The researchers' investigation of anti-angiogenic drugs provides valuable insights into the potential for these therapies to effectively disrupt tumor development and improve patient outcomes.

Dr.Camel's Conclusion

This research provides a valuable roadmap for navigating the complex terrain of gastric cancer treatment, highlighting the potential of anti-angiogenic therapies to effectively disrupt tumor growth and improve patient outcomes. The study's comparative analysis offers insights into the potential of each drug and underscores the importance of personalized treatment approaches tailored to individual patient needs.

Date :
  1. Date Completed 2020-04-09
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

32035930

DOI: Digital Object Identifier

10.1016/j.lfs.2020.117402

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・Side Effects of cabozantinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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