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Selective RAR agonists for acne vulgaris: A narrative review.

Author: AbdelmaksoudAyman, GaladariHassan, GoldustMohamad, GrabbeStephan, GuptaMrinal, KaragaiahPriyanka, KassirMartin, KatsambasAndreas, LottiTorello, SonthaliaSidharth, WollinaUwe

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Acne vulgaris is a chronic inflammatory skin disease that affects adolescents and adults. The pathogenesis of acne involves abnormalities in sebum production, follicular plugging, proliferation of Propionibacterium acnes, and chronic inflammation.
Paper Details　
Original Abstract of the Article :
Acne vulgaris is a chronic disfiguring inflammatory disease of adolescents and adults affecting up to 90% of the population around the world. The sequence of etiopathogenesis in acne is not completely understood but involves abnormalities in sebum production, follicular plugging, proliferation of pr...See full text at original site
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引用元：
https://doi.org/10.1111/jocd.13340

データ提供：米国国立医学図書館（NLM）

Targeting Acne Vulgaris with Selective RAR Agonists

Acne vulgaris, a common skin condition that can be a source of frustration and self-consciousness, can be a challenging desert landscape to navigate. This review explores the potential of [selective RAR agonists], a class of drugs that target the retinoic acid receptor, as a treatment for acne vulgaris. The researchers discuss the underlying mechanisms of acne vulgaris and the potential benefits of selective RAR agonists in addressing these mechanisms.

A New Oasis for Acne Vulgaris Treatment

This review suggests that selective RAR agonists could be a promising new approach to treating acne vulgaris. The researchers highlight the potential of these drugs to address key aspects of acne pathogenesis, including sebum production, follicular plugging, and inflammation. Further research is needed to fully evaluate their effectiveness, but the potential benefits are promising.

Finding Clear Skin: A Journey to Confidence

This review provides a valuable overview of the potential of selective RAR agonists as a treatment for acne vulgaris. It offers a glimpse into the future of acne management, potentially paving the way for new and effective treatment options. It is a reminder that even in the challenging landscape of skin conditions, there can be oases of hope and effective treatment.

Dr. Camel's Conclusion

This review delves into the intriguing potential of selective RAR agonists as a treatment for acne vulgaris. It's a reminder that the pursuit of clear skin can be a journey, and like a camel navigating a vast desert, we must be patient and persistent in seeking new solutions. Selective RAR agonists may be a valuable oasis in our quest for healthy and radiant skin.

Date :
  1. Date Completed 2021-02-05
  2. Date Revised 2021-02-05
Further Info :

Pubmed ID

32100454

DOI: Digital Object Identifier

10.1111/jocd.13340

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English

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