Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model.

Author: BayatliNur, GurSerap, Kaya-SezginerEcem, LokmanUtku, OztekinCetin Volkan, Yilmaz-OralDidem

Paper Details 
Original Abstract of the Article :
AIMS: To evaluate the impacts of hydrogen sulfide (H METHODS: Sprague-Dawley rats were equally divided into five groups: (a) sham-operated control; (b) PBOO; (c) PBOO-treated with NaHS (5.6 mg/kg/day, ip); (d) PBOO-treated with tadalafil (2 mg/kg/day, oral); and (e) PBOO-treated with combination of...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/nau.24333

データ提供:米国国立医学図書館(NLM)

Combating Erectile Dysfunction: A Two-Pronged Attack

This study explores the potential of combining two different medications for treating erectile dysfunction (ED), a condition that affects the ability to achieve and maintain an erection. Imagine a desert oasis with a dried-up riverbed, unable to provide the essential water for life. This study investigates a strategy to restore the flow of water, or in this case, blood flow, to the affected region.

Restoring the Oasis's Life Force

The researchers studied the effects of combining sodium hydrogen sulfide (NaHS), a compound that can help relax blood vessels, and tadalafil, a medication that enhances blood flow, in rats with partial bladder outlet obstruction, a condition that can lead to ED. They discovered that this combined treatment was significantly more effective than either medication alone in restoring blood flow, essentially reviving the oasis's life force.

Finding the Right Combination for Optimal Health

This study suggests that combining different therapies could offer a more effective approach to treating ED. It's like finding the perfect blend of desert plants and water sources to create a thriving oasis. This research encourages further investigation into combination therapies for optimizing treatment outcomes for those facing ED.

Dr. Camel's Conclusion

This study is a beacon of hope for those battling ED. Like a desert wanderer discovering a hidden spring, the researchers have uncovered a potential solution for restoring function and improving quality of life. This combination therapy, like a well-planned oasis, offers a promising approach to re-energizing and revitalizing the body's natural mechanisms.
Date :
  1. Date Completed 2020-11-13
  2. Date Revised 2020-11-13
Further Info :

Pubmed ID

32150290

DOI: Digital Object Identifier

10.1002/nau.24333

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.