Extending cytomegalovirus prophylaxis in high-risk (D+/R-) lung transplant recipients from 6 to 9 months reduces cytomegalovirus disease: A retrospective study.

Author: BinnieMatthew, ChaparroCecilia, ChowChung-Wai, HerreraSabina, HusainShahid, KeshavjeeShaf, KhanBasha, MartinuTereza, SingerLianne G, TikkanenJussi M, TomlinsonGeorge

Paper Details 
Original Abstract of the Article :
Cytomegalovirus (CMV)-seronegative recipients receiving a seropositive allograft (D+/R-) are at a high risk of developing CMV disease. Our program increased the duration of CMV prophylaxis from 6 to 9 months in May 2013. Here, we present the impact on the incidence of CMV infection, disease, side ef...See full text at original site
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引用元:
https://doi.org/10.1111/tid.13277

データ提供:米国国立医学図書館(NLM)

Extending CMV Prophylaxis in Lung Transplant Recipients: Preventing Disease in a High-Risk Desert

Lung transplantation, a life-saving procedure for individuals with end-stage lung disease, carries its own set of risks. This research delves into the management of cytomegalovirus (CMV) infection in lung transplant recipients, specifically those who are CMV-seronegative but receive a seropositive allograft (D+/R-). The researchers investigated the impact of extending CMV prophylaxis from 6 months to 9 months in this high-risk group. They retrospectively analyzed data on lung transplant recipients, comparing the incidence of CMV infection, disease, side effects, rejection, and other relevant parameters between the two prophylaxis durations. The findings revealed that extending CMV prophylaxis to 9 months significantly reduced the incidence of CMV disease in these high-risk patients, highlighting the potential benefits of longer-term prophylaxis.

A Shield in the Desert: Extending Prophylaxis to Combat CMV Disease

This study provides compelling evidence for the effectiveness of extending CMV prophylaxis to 9 months in lung transplant recipients who are CMV-seronegative but receive a seropositive allograft. The researchers found a significant reduction in the incidence of CMV disease, demonstrating the potential of longer-term prophylaxis to improve patient outcomes and reduce the risk of this potentially serious complication. The study emphasizes the importance of individualized risk assessment and tailored prophylaxis strategies to optimize patient care in lung transplantation.

Navigating the Desert of Transplant Complications: Protecting Patients

This research offers valuable insights for healthcare professionals involved in lung transplantation. The study's findings highlight the potential benefits of extending CMV prophylaxis in high-risk patients, suggesting a more robust approach to preventing this common complication. However, it is essential to consult with a qualified medical professional to determine the most appropriate prophylaxis strategy based on individual needs and medical history.

Dr.Camel's Conclusion

This study offers a beacon of hope in the desert of lung transplant complications, demonstrating the potential of extending CMV prophylaxis to reduce the risk of disease. The research highlights the importance of proactive strategies and personalized care in managing the complex challenges associated with organ transplantation.

Date :
  1. Date Completed 2021-06-07
  2. Date Revised 2021-06-07
Further Info :

Pubmed ID

32170813

DOI: Digital Object Identifier

10.1111/tid.13277

Related Literature

SNS
PICO Info
in preparation
Languages

English

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