Paper Details

  1. Home
  2. Paper Details

Lorcaserin Administration has Pro-Ejaculatory Effects in Rats via 5-HT<sub>2C</sub> Receptors Activation: A Putative Pharmacologic Strategy to Delayed Ejaculation?

Author: AntunesEdson, KempinasWilma de Grava, PachecoTainá Louise, de Almeida KigutiLuiz Ricardo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lorcaserin is an anti-obesity drug that activates 5-HT<sub>2C</sub> receptors. The 5-HT<sub>2C</sub> receptor is involved in ejaculation control. However, no data exists on the potential effect of lorcaserin on ejaculation.
Paper Details　
Original Abstract of the Article :
Label="BACKGROUND">Lorcaserin is an anti-obesity drug whose weight loss effect results from 5-hydroxytryptamin (5-HT)<sub>2C</sub> receptors activation. The 5-HT<sub>2C</sub> receptor was shown to participate in the physiological control of ejaculation, but no data addressing a putative effect of lo...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jsxm.2020.02.027

データ提供：米国国立医学図書館（NLM）

Lorcaserin: A Potential Solution for Delayed Ejaculation

We're exploring the exciting potential of lorcaserin, an anti-obesity drug, for a surprising new application: treating delayed ejaculation. This study investigates the pro-ejaculatory effects of lorcaserin in rats, focusing on its activation of 5-HT2C receptors. The researchers propose that lorcaserin could be a valuable pharmacological strategy for addressing this common sexual dysfunction.

Beyond Weight Loss: Lorcaserin's Potential for Sexual Health

The study's findings suggest that lorcaserin's action on 5-HT2C receptors might be responsible for its pro-ejaculatory effects. This discovery opens up new possibilities for using this existing drug to address a distinct health concern. Further research is needed to validate these findings in humans and to explore the optimal dosing and safety profiles for this novel application of lorcaserin.

A New Frontier in Sexual Health: Lorcaserin's Promise

The potential of lorcaserin to treat delayed ejaculation is a promising development in the field of sexual health. If further studies confirm its efficacy and safety, this drug could provide a valuable new treatment option for individuals struggling with this condition. This research highlights the importance of considering the potential applications of existing drugs for new therapeutic purposes.

Dr.Camel's Conclusion

Just as a camel's endurance allows it to traverse vast deserts, lorcaserin's potential to address delayed ejaculation represents a journey into uncharted territory, seeking to alleviate a condition that can significantly impact an individual's well-being.

Date :
  1. Date Completed 2020-12-21
  2. Date Revised 2020-12-21
Further Info :

Pubmed ID

32234370

DOI: Digital Object Identifier

10.1016/j.jsxm.2020.02.027

Related Literature

Article Analysis
・Effects of lorcaserin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.