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Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis.

Author: GuLuosha, MaJianxun, QinZelian, WangPu, WangQifei

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Nitroglycerin (NTG) ointment significantly reduced the rates of mastectomy flap necrosis and other complications. There was no significant difference in drug-related adverse reactions.
Paper Details　
Original Abstract of the Article :
Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it. However, it is not clear whether topical NTG can completely prevent the occurrence of flap necrosis after breast cancer surgery, and it is also unclear whether this treat...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174291/

データ提供：米国国立医学図書館（NLM）

Mastectomy Flap Necrosis: A Desert of Challenges in Breast Cancer Treatment

Breast cancer surgery can be a challenging desert journey for patients, with the potential for complications such as flap necrosis, where the skin flap used to cover the surgical site dies. This research delves into the potential benefits and safety of topical nitroglycerin (NTG) in preventing this debilitating complication. The study, like a dedicated guide, navigates the complex landscape of breast cancer recovery, seeking to understand the role of NTG in promoting healing and minimizing risks.

Nitroglycerin: A Potential Oasis in the Flap Necrosis Desert

The study's findings, like a shimmering oasis in the desert, suggest that topical NTG can significantly reduce the risk of flap necrosis after mastectomy. The meta-analysis of multiple studies reveals a consistent benefit, highlighting the potential of NTG to enhance wound healing and minimize complications. This discovery offers a glimmer of hope for patients undergoing breast cancer surgery, potentially reducing the likelihood of this challenging complication.

Navigating the Desert of Breast Cancer Recovery

This research provides valuable insights into the complex terrain of breast cancer recovery. The findings suggest that topical NTG may be a helpful tool in preventing flap necrosis, offering a potential path to smoother healing and a faster recovery. This knowledge empowers patients and their doctors to make informed decisions regarding post-operative care, navigating the desert of breast cancer recovery with greater confidence and hope for a successful outcome.

Dr.Camel's Conclusion

This research offers a valuable oasis in the desert of breast cancer recovery. The study's findings suggest that topical nitroglycerin can significantly reduce the risk of flap necrosis, offering a potential path to smoother healing and a faster recovery. As we continue to explore the complex landscape of breast cancer treatment, this research provides a glimmer of hope and a valuable resource for patients and their doctors.

Date :
  1. Date Completed 2020-11-30
  2. Date Revised 2021-04-21
Further Info :

Pubmed ID

32317705

DOI: Digital Object Identifier

PMC7174291

Related Literature

Article Analysis
・Side Effects of nitroglycerin topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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