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Effects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms.

Author: CacciapuotiGiovanna, CarrieroMaria Vincenza, MinopoliMichele, MoscaLaura, PaganoMartina, PorcelliMarina, VitielloFrancesca

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the effects of S-Adenosyl-L-methionine (AdoMet) on the growth and spread of head and neck squamous cell carcinoma (HNSCC). AdoMet was found to inhibit cell cycle progression, migration, and invasion of HNSCC cells. The study suggests that AdoMet may be a promising candidate for future drug development against metastatic HNSCC.
Paper Details　
Original Abstract of the Article :
S‑Adenosyl‑L‑methionine (AdoMet) is the principal methyl donor in transmethylation reactions fundamental to sustaining epigenetic modifications. Over the past decade, AdoMet has been extensively investigated for its anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in several types of huma...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115356/

データ提供：米国国立医学図書館（NLM）

S-Adenosyl-L-methionine: A New Weapon in the Fight Against Head and Neck Cancer

Head and neck squamous cell carcinoma (HNSCC), a type of cancer that often spreads aggressively, is like a wildfire raging through the desert. This study explores the potential of S-adenosyl-L-methionine (AdoMet), a naturally occurring compound, as a new weapon against this aggressive cancer. It's like discovering a potent antidote to fight the fire.

AdoMet: A Multi-pronged Attack

The research shows that AdoMet can inhibit the growth, migration, and invasion of HNSCC cells. It's like using a combination of strategies to contain a wildfire. This suggests that AdoMet may have a significant role in preventing metastasis and improving patient outcomes.

Hope for a Better Future

The study highlights the potential of AdoMet as a promising therapeutic agent for HNSCC. This discovery could lead to new treatment options and improve the lives of patients battling this challenging disease. It's like finding a sustainable solution to fight the wildfire and protect the precious landscape.

Dr.Camel's Conclusion

This research offers a glimmer of hope in the fight against head and neck squamous cell carcinoma. AdoMet, a naturally occurring compound, demonstrates a promising ability to inhibit cancer cell growth and metastasis, suggesting a new path towards effective treatments. This discovery encourages us to explore the potential of naturally derived agents in combating cancer and to continue searching for solutions that can improve the lives of patients facing this formidable disease.
Date :
  1. Date Completed 2021-02-08
  2. Date Revised 2021-09-16
Further Info :

Pubmed ID

32319579

DOI: Digital Object Identifier

PMC7115356

SNS
PICO Info
in preparation
Languages

English

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