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Multiple occurrence of premature polyarticular osteoarthritis in an early medieval Bohemian cemetery (Prague, Czech Republic).

Author: CvrčekJan, Drtikolová KaupováSylva, DžupaValér, KackiSacha, KuželkaVítězslav, LabošMarek, NěmečkováAlena, TomkováKateřina, VelemínskýPetr, ZazvonilováEliška

Historical ArticleA research paper that analyzes past events and developments using primary sources and examines them from a historical perspective.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Four adults under the age of 50 from a medieval skeletal collection in Prague, Czechia, showed signs of early-onset degenerative joint disease. All four individuals had multiple symmetrical degenerative changes affecting most of their joints, as well as associated dysplastic deformities including bilateral hip dysplasia, flattening of the femoral condyles, and deformed elbows. Their diet differed from the contemporary population. The findings suggest a mild form of skeletal dysplasia, possibly multiple epiphyseal dysplasia or type-II collagenopathy, as the cause of premature osteoarthritis.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To highlight conditions that may cause early-onset degenerative joint disease, and to assess the possible impact of such diseases upon everyday life. MATERIAL: Four adults aged under 50 years from a medieval skeletal collection of Prague (Czechia). METHODS: Visual, osteometric, X-ray, ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.ijpp.2020.04.004

データ提供：米国国立医学図書館（NLM）

Unveiling the Mysteries of Premature Osteoarthritis in an Early Medieval Cemetery

The study of ancient remains, like uncovering ancient ruins in the desert, can reveal fascinating insights into the health and well-being of past populations. This research examines skeletal evidence of premature polyarticular osteoarthritis in an early medieval Bohemian cemetery. The study aims to identify potential causes of early-onset degenerative joint disease and to assess its impact on daily life.

The researchers analyzed the skeletal remains of four individuals under 50 years old, discovering evidence of multiple symmetrical degenerative changes affecting the majority of joints. They also noted associated dysplastic deformities, suggesting a possible link between skeletal dysplasia and premature osteoarthritis. This is like finding a trail of footprints leading to a hidden oasis, revealing a connection between different aspects of the past.

Exploring the Roots of Osteoarthritis: A Journey Through the Past

This research sheds light on the complex interplay between skeletal dysplasia and premature osteoarthritis. The findings suggest that individuals with certain types of dysplasia may be at increased risk of developing early-onset osteoarthritis. This knowledge is crucial for understanding the causes and progression of osteoarthritis, potentially leading to new diagnostic and therapeutic strategies.

Understanding the Impact of Osteoarthritis: A Window into the Past

This study reminds us that the study of ancient remains can provide valuable insights into the health and well-being of past populations. By understanding the causes and impact of osteoarthritis in the past, we can gain a better understanding of this debilitating condition and potentially improve treatment and prevention strategies in the present.

Dr. Camel's Conclusion

This fascinating study offers a glimpse into the health challenges faced by individuals in the past. By examining the skeletal remains of individuals with premature osteoarthritis, researchers have uncovered valuable insights into the complex interplay between skeletal dysplasia and joint degeneration. This research serves as a reminder that the study of the past can help us understand and address health concerns in the present.

Date :
  1. Date Completed 2021-10-18
  2. Date Revised 2021-10-18
Further Info :

Pubmed ID

32417673

DOI: Digital Object Identifier

10.1016/j.ijpp.2020.04.004

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English

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