Drug-Related Cutaneous Adverse Events in Philadelphia Chromosome-Negative Myeloproliferative Neoplasms: A Literature Review.

Author: GuglielmelliPaola, MalatoAlessandra, PalumboGiuseppe Alberto, PuglieseNovella, RossiElena

Paper Details 
Original Abstract of the Article :
Since myeloproliferative neoplasms (MPN) pose a significant risk for vascular and thrombotic complications, cytoreductive therapies, such as hydroxyurea (HU), interferon (IFN) inhibitors, and Janus kinase (JAK) inhibitors are recommended for patients at high risk. However, these agents also place pa...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312244/

データ提供:米国国立医学図書館(NLM)

Skin Toxicity: A Hidden Desert in Myeloproliferative Neoplasm Treatment

Navigating the [myeloproliferative neoplasms (MPN)] landscape often involves a complex interplay of [cytoreductive therapies] and their potential side effects. This study, like a seasoned explorer, explores the often-overlooked terrain of [drug-related cutaneous adverse events] associated with these treatments. The study delves into the literature on skin toxicity related to the use of drugs for treating MPN, revealing a potential desert of complications that require careful attention. Researchers highlight the importance of thorough skin examinations and detailed patient history to mitigate these risks.

Skin Toxicity: A Potential Pitfall in MPN Treatment

The study reveals that while cytoreductive agents are generally well tolerated, they can still cause skin toxicity, including [granulocytopenia], [anemia], [thrombocytopenia], and even increased risk for [basal cell carcinoma (BCC)] and [squamous cell carcinoma (SCC)]. This underscores the importance of close monitoring and proactive management of potential skin complications in patients receiving these treatments.

Protecting Your Skin: Navigating the Desert of MPN Treatment

The study emphasizes the importance of vigilance in managing skin health during MPN treatment. Regular skin examinations and a detailed patient history can help identify and address potential skin problems early on, potentially preventing serious complications. It's crucial to be aware of the potential risks and work closely with healthcare professionals to ensure optimal care.

Dr.Camel's Conclusion

This study serves as a reminder that even the most effective MPN treatments can have unexpected side effects. It highlights the importance of careful monitoring for skin toxicity, including regular skin examinations and a detailed patient history. By being vigilant about skin health, patients can navigate the desert of MPN treatment with greater confidence and minimize the risk of potential complications.

Date :
  1. Date Completed 2021-03-30
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

32486130

DOI: Digital Object Identifier

PMC7312244

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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