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Effects of cryotherapy on high-dose melphalan-induced oral mucositis in pediatric patients undergoing autologous stem cell transplantation.
Author: AdachiSouichi, HiramatsuHidefumi, HorikoshiYasuo, KatoItaru, KawaguchiKoji, OguraTaemi, SaidaSatoshi, TakachiTakayuki, TakitaJunko, UmedaKatsutsugu, WatanabeKenichiro
Original Abstract of the Article :
Cryotherapy is a conventional method for preventing melphalan-induced oral mucositis (OM) in adult patients. We retrospectively examined the clinical benefits of cryotherapy in 41 pediatric patients undergoing autologous stem cell transplantation using a melphalan-etoposide-carboplatin regimen. Twen...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://doi.org/10.1002/pbc.28495
データ提供:米国国立医学図書館(NLM)
Cryotherapy: A Cooling Down Approach to Melphalan-Induced Oral Mucositis
Melphalan-induced oral mucositis, a painful side effect of chemotherapy, can significantly impact the quality of life for patients undergoing treatment. This study explores the effectiveness of cryotherapy, a technique involving cold therapy, in preventing or mitigating this side effect in pediatric patients receiving high-dose melphalan for autologous stem cell transplantation.
The study's retrospective design, like a careful examination of historical records by an archaeologist, analyzed data from 41 pediatric patients who received autologous stem cell transplantation. Researchers meticulously compared the incidence and severity of oral mucositis in patients who received cryotherapy with those who did not.
The findings, like a refreshing oasis in the desert of chemotherapy side effects, suggest that cryotherapy could be a valuable tool for managing melphalan-induced oral mucositis in pediatric patients.
Cryotherapy: A Cooling Down Approach to Oral Mucositis
The study demonstrated a significant reduction in the incidence and severity of oral mucositis in pediatric patients who received cryotherapy, highlighting its potential as a preventative measure against this debilitating side effect.
This finding, like a beacon of hope in the desert of chemotherapy side effects, underscores the importance of exploring alternative approaches to managing treatment-related complications.
Navigating the Desert of Side Effects: Finding Relief Through Cooling
This research encourages us to consider the potential of cryotherapy, like a refreshing oasis in the desert of chemotherapy side effects, as a valuable tool for managing oral mucositis in pediatric patients undergoing high-dose melphalan treatment.
It also highlights the importance of ongoing research in this field, seeking to develop new and effective therapies that can mitigate the side effects of cancer treatment and improve patient quality of life.
Dr.Camel's Conclusion
This study provides compelling evidence supporting the use of cryotherapy for preventing or mitigating melphalan-induced oral mucositis in pediatric patients undergoing autologous stem cell transplantation, offering a potential solution for managing this challenging side effect.
Date :
- Date Completed 2020-12-07
- Date Revised 2020-12-14
Further Info :
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