Treatment of hyperlipidemia with proprotein convertase subtilisin/kexin type 9 inhibitor in a patient with nephrotic syndrome: a case report.

Author: BaeEun Hui, ChoiHong Sang, KimChang Seong, KimSoo Wan, MaSeong Kwon

Paper Details 
Original Abstract of the Article :
We report the case of a patient with nephrotic syndrome and toxic epidermal necrolysis (TEN) caused by statin use. The associated hyperlipidemia was controlled using proprotein convertase subtilisin/ kexin type 9 (PCSK9) inhibitors. This is a unique case of treating hyperlipidemia with PCSK9 inhibit...See full text at original site
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引用元:
https://doi.org/10.21037/apm-19-587

データ提供:米国国立医学図書館(NLM)

PCSK9 Inhibitors: A Potential Oasis for Statin Intolerance

Hyperlipidemia, or high cholesterol, can be a challenging desert to navigate, especially when traditional treatments like statins prove ineffective or cause unwanted side effects. This case report presents a unique scenario involving a patient with nephrotic syndrome who experienced a severe skin reaction to statins. The researchers explored an alternative approach using a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, a newer class of medication for managing high cholesterol.

A Promising Alternative for Statin Intolerance

The case report demonstrates the potential of PCSK9 inhibitors as an effective alternative treatment for patients who cannot tolerate statins. The patient in this study experienced a significant improvement in their hyperlipidemia after switching to a PCSK9 inhibitor, highlighting the potential of this medication for patients facing specific challenges. While further research is needed, this case report suggests a promising avenue for personalized treatment approaches.

Navigating the Desert of High Cholesterol

The study emphasizes the importance of personalized treatment approaches for managing high cholesterol. For patients who struggle with statins, PCSK9 inhibitors may offer a valuable alternative, potentially improving cholesterol levels while minimizing side effects. This case report serves as a beacon of hope for individuals seeking safe and effective solutions for managing hyperlipidemia.

Dr.Camel's Conclusion

This case report, like a shimmering oasis in the desert, offers a glimmer of hope for patients struggling with hyperlipidemia and statin intolerance. PCSK9 inhibitors may offer a new path towards better management of this common condition, allowing patients to navigate the desert of high cholesterol with greater ease.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

32648458

DOI: Digital Object Identifier

10.21037/apm-19-587

Related Literature

SNS
PICO Info
in preparation
Languages

English

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