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Predictors of Time to Discontinuation of Levodopa-Carbidopa Intestinal Gel Infusion: A Retrospective Cohort Study.

Author: DrentMartje, Groenendal-LaurensseJerney W M J, MoesHarmen R, TissinghGerrit, van LaarTeus

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study focuses on identifying prognostic factors that influence the duration of levodopa-carbidopa intestinal gel (LCIG) treatment in patients with advanced Parkinson’s disease. LCIG is a continuous infusion therapy that provides sustained dopamine delivery, but its effectiveness varies between individuals. Understanding prognostic factors can help optimize patient selection for LCIG therapy.
Paper Details　
Original Abstract of the Article :
Continuous intra-duodenal infusion of levodopa-carbidopa intestinal gel (LCIG) is a well-established therapy for patients with advanced Parkinson's disease (PD) suffering from motor complications despite optimized treatment with oral dopaminomimetics. However, time to discontinuation of treatment wi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458507/

データ提供：米国国立医学図書館（NLM）

Predicting Treatment Duration for Levodopa-Carbidopa Intestinal Gel Infusion

This research explores the realm of [Parkinson's Disease Treatment], focusing on the use of continuous intra-duodenal infusion of levodopa-carbidopa intestinal gel (LCIG) for managing advanced Parkinson's disease (PD) and its associated motor complications. The study investigated factors that influence the duration of LCIG treatment, aiming to better predict patient outcomes and optimize treatment selection.

Understanding the Factors Influencing LCIG Treatment Duration

This research identifies factors that impact the duration of LCIG treatment in patients with advanced PD. By identifying these factors, researchers can better predict patient outcomes and optimize treatment selection. This research highlights the importance of personalized medicine in managing PD and ensuring the most effective treatment for each individual.

Tailoring Treatment for Parkinson's Disease

Just like a camel navigating a desert needs to choose the right path, patients with Parkinson's disease require a personalized approach to treatment. This research emphasizes the need for carefully considering individual factors to optimize treatment selection and ensure the best possible outcomes.

Dr. Camel's Conclusion

This study sheds light on the factors influencing the duration of LCIG treatment for Parkinson's disease. The research encourages further investigation into personalized treatment strategies for PD, aiming to improve patient outcomes and enhance the quality of life for individuals living with this complex condition.

Date :
  1. Date Completed 2021-08-19
  2. Date Revised 2021-08-19
Further Info :

Pubmed ID

32675420

DOI: Digital Object Identifier

PMC7458507

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・Side Effects of levodopa and carbidopa
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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