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Lower Extremity Non-Blanchable Purpura Secondary to Methotrexate Toxicity: A Case Report.
Author: MateenSara, PontiousJane
Original Abstract of the Article :
Methotrexate is an antimetabolite drug that works as a folic acid analogue to inhibit DNA synthesis. This drug is commonly used for treating conditions such as psoriasis, rheumatoid arthritis, atopic dermatitis, and collagen disease. Although methotrexate may have common adverse effects such as bone...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1053/j.jfas.2020.03.022
データ提供:米国国立医学図書館(NLM)
Methotrexate Toxicity: A Case Study in the Desert of Dermatology
The practice of dermatology is a vast and intricate desert, where clinicians are constantly navigating the complex interplay of medications and skin reactions. This case report explores the rare but serious side effect of lower extremity non-blanchable purpura secondary to methotrexate toxicity. The authors present a compelling case of a patient who developed this unusual complication, highlighting the importance of careful monitoring and early detection of potential adverse events.
A Rare Oasis of Knowledge: Understanding Methotrexate Toxicity
The case report underscores the potential for unexpected side effects of medications, even those commonly used and generally well-tolerated. The authors emphasize the need for thorough history taking and physical examination to properly diagnose and manage potential drug-related complications. This case study serves as a valuable reminder of the complexities of drug interactions and the importance of vigilance in clinical practice.
Navigating the Desert of Dermatology: Vigilance and Early Detection
This case report reinforces the importance of proactive monitoring and early detection of potential adverse drug reactions. Healthcare professionals are encouraged to stay vigilant and to consult with specialists when necessary to ensure the safe and effective use of medications, especially those with potentially serious side effects.
Dr. Camel's Conclusion
In the vast and unpredictable desert of dermatology, even seemingly familiar medications can surprise us with unexpected side effects. This case report serves as a valuable reminder to approach patient care with meticulous attention to detail, careful monitoring, and open communication. By navigating this complex terrain with vigilance and expertise, we can ensure the safety and well-being of our patients.
Date :
- Date Completed 2021-06-24
- Date Revised 2021-06-24
Further Info :
Related Literature
English
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