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Freeze-all versus fresh blastocyst transfer strategy during in vitro fertilisation in women with regular menstrual cycles: multicentre randomised controlled trial.

Author: AndersenAnders Nyboe, BerghChristina, BogstadJeanette, HumaidanPeter, JeppesenJanni Vikkelsø, KhatibiAli, KitlinskiMargaretha Laczna, LøsslKristine, MikkelsenAnne Lis, NielsenHenriette Svarre, PinborgAnja, PolyzosNikolaos P, PrætoriusLisbeth, SkoubySven O, SopaNegjyp, SpangmoseAnne Lærke, StormlundSacha, ZedelerAnne, ZiebeSøren, la Cour FreieslebenNina

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This multicentre, randomised controlled trial compared the ongoing pregnancy rate between a freeze-all strategy and a fresh transfer strategy in assisted reproductive technology treatment. 460 women with regular menstrual cycles were randomized to elective freezing of all embryos (freeze-all) or single blastocyst transfer in the fresh cycle (fresh transfer). No significant difference was observed in ongoing pregnancy rate or live birth rate between the two groups.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare the ongoing pregnancy rate between a freeze-all strategy and a fresh transfer strategy in assisted reproductive technology treatment. DESIGN: Multicentre, randomised controlled superiority trial. SETTING: Outpatient fertility clinics at eight public hospitals in Denmark, Swed...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399608/

データ提供：米国国立医学図書館（NLM）

Freeze-All vs. Fresh Blastocyst Transfer: Exploring Optimal Strategies for IVF

In vitro fertilization (IVF) is a complex and often emotionally charged journey. This study compares the effectiveness of two different IVF strategies: freeze-all and fresh transfer. The researchers conducted a multicenter randomized controlled trial involving 460 women with regular menstrual cycles. The study found that the ongoing pregnancy rate did not differ significantly between the two groups. This suggests that in women with regular cycles, a freeze-all strategy, where all embryos are frozen and transferred in a subsequent cycle, may not be superior to a fresh transfer strategy, where embryos are transferred in the same cycle.

A Closer Look at IVF Strategies

This study adds to the ongoing debate about the optimal approach to IVF. The findings suggest that while freeze-all may be a safe option for women with a higher risk of ovarian hyperstimulation syndrome, it may not be necessary for all women.

Making Informed Decisions about IVF

The camel knows that IVF is a personal journey, and the best approach can vary depending on individual circumstances. This study offers valuable insights into the effectiveness of different IVF strategies. It's crucial to have an open and honest conversation with your doctor to discuss your individual needs and goals.

Dr.Camel's Conclusion

This study provides valuable insights into the ongoing debate about the best approach to IVF. The camel recognizes the complexity of IVF and the importance of personalized care. The research highlights the need for careful consideration of individual factors, including the risk of ovarian hyperstimulation syndrome, when choosing between freeze-all and fresh transfer strategies.

Date :
  1. Date Completed 2020-08-17
  2. Date Revised 2020-08-18
Further Info :

Pubmed ID

32759285

DOI: Digital Object Identifier

PMC7399608

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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