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Comparison of the effect of clarithromycin triple therapy with or without <i>N</i>-acetylcysteine in the eradication of <i>Helicobacter pylori</i>: a randomized controlled trial.
Author: , BairMing-Jong, ChangChi-Yang, ChenChi-Yi, ChenChieh-Chang, ChenMei-Jyh, ChenPo-Yueh, ChiuMin-Chin, ChouChu-Kuang, FangYu-Jen, HsiehCheng-Lin, HsuWen-Feng, HsuYao-Chun, HuWen-Hao, KuoChia-Chi, LeeJi-Yuh, LeeYi-Chia, LiouJyh-Ming, LiuTzeng-Ying, LuoJiing-Chyuan, ShunChia-Tung, TsaiMin-Horn, TsengCheng-Hao, WuMing-Shiang, YangTsung-Hua, YuJian-Jyun
Original Abstract of the Article :
Label="BACKGROUND" NlmCategory="BACKGROUND">Whether adjunctive <i>N</i>-acetylcysteine (NAC) may improve the efficacy of triple therapy in the first-line treatment of <i>Helicobacter pylori</i> infection remains unknown. Our aim was to compare the efficacy of 14-day triple therapy with or without NA...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406927/
データ提供：米国国立医学図書館（NLM）
Helicobacter pylori Eradication: A Quest for Better Treatment in the Desert of Gastric Infections
Helicobacter pylori (H. pylori) is a bacteria that can colonize the stomach, leading to various gastric diseases. Triple therapy, a combination of antibiotics and a proton pump inhibitor, is commonly used to eradicate H. pylori infection. This study explores the potential of adjunctive N-acetylcysteine (NAC) to enhance the efficacy of triple therapy. The authors conducted a randomized controlled trial to compare the effectiveness of triple therapy with or without NAC, seeking to find a more potent weapon against this persistent foe.
Navigating the Shifting Sands of Treatment Efficacy
The study's results shed light on the potential of NAC to improve the efficacy of triple therapy for H. pylori eradication. While the study did not find a significant difference in eradication rates between the two groups, the findings provide valuable insights into the complex interplay between NAC and triple therapy. Further research is needed to determine the optimal role of NAC in the treatment of H. pylori infections.
A New Oasis in the Desert of Gastric Infections
This research offers a glimpse into a potential new oasis in the desert of gastric infections. NAC may play a role in optimizing treatment strategies for H. pylori, a prevalent bacteria that can cause a range of gastric diseases. Continued exploration of NAC's potential in this area could lead to more effective and targeted treatments for patients infected with H. pylori.
Dr.Camel's Conclusion
The quest for a more effective treatment for H. pylori infection continues in the desert of gastric diseases. This study, while not conclusive, provides valuable insights into the potential of NAC to enhance the efficacy of triple therapy. The findings encourage further research in this area, with the hope of finding a more potent weapon against this persistent foe.
Date :
- Date Completed n.d.
- Date Revised 2022-04-16
Further Info :
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