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Effects of CAPTEM (Capecitabine and Temozolomide) on a Corticotroph Carcinoma and an Aggressive Corticotroph Tumor.

Author: ChikConstance L, EasawJay, InoshitaNaoko, MehtaVivek, Nakano-TatenoTae, SatouMotoyasu, TatenoToru, van LandeghemFrank K H

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Overview

This study describes the use of capecitabine and temozolomide (CAPTEM) in two patients with resistant corticotroph tumors and carcinomas, demonstrating potential efficacy and tumor control.
Paper Details　
Original Abstract of the Article :
Corticotroph carcinomas and aggressive corticotroph tumors can be resistant to conventional therapy, including surgery, radiotherapy, and medical treatment. Recent evidence suggests that temozolomide (an oral alkylating agent) administered with capecitabine (pro-drug of 5-fluorouracil) may improve p...See full text at original site
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引用元：
https://doi.org/10.1007/s12022-020-09647-w

データ提供：米国国立医学図書館（NLM）

CAPTEM: A Potential Oasis for Resistant Corticotroph Tumors

Corticotroph tumors, a type of pituitary tumor, can be challenging to treat, like navigating a treacherous desert. This study investigates the effectiveness of a novel treatment approach for these tumors.

Researchers explored the use of CAPTEM (capecitabine and temozolomide), a combination therapy, in treating two patients with corticotroph tumors. Both patients had previously undergone surgery and radiation therapy. The results showed that CAPTEM led to tumor control and improvement in both patients, suggesting that it could be a valuable option for patients with resistant corticotroph tumors.

CAPTEM: A New Oasis in the Treatment Landscape

This study offers hope for individuals with corticotroph tumors that are resistant to conventional therapies. CAPTEM, a novel combination therapy, showed promising results in controlling tumor growth and improving patient outcomes. Further research is needed to confirm its effectiveness in a larger population, but the findings suggest that it could be a significant advance in treating these challenging tumors.

Navigating the Desert of Pituitary Tumors: Finding the Right Path

Individuals with pituitary tumors should consult with a healthcare professional to discuss appropriate treatment options. Treatment plans are often individualized and may involve surgery, radiation therapy, and/or medication. It is crucial to work closely with your healthcare provider to find the best course of treatment for your specific needs.

Dr.Camel's Conclusion

CAPTEM, a combination therapy, may offer a potential oasis in the desert of resistant corticotroph tumors. While more research is needed, its promising results suggest that it could be a valuable tool for managing these challenging tumors. Remember, seeking professional guidance and understanding your treatment options are essential for navigating this complex health journey.

Date :
  1. Date Completed 2022-01-17
  2. Date Revised 2022-01-17
Further Info :

Pubmed ID

32833164

DOI: Digital Object Identifier

10.1007/s12022-020-09647-w

Related Literature

Article Analysis
・Effects of capecitabine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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