High viral load predicts virologic failure in chronic genotype 2 hepatitis C virus-infected patients receiving glecaprevir/pibrentasvir therapy.

Author: ChangTe-Sheng, ChenWei-Ming, ChiuWen Nan, HsiehYung-Yu, HuJin Hung, HungChao-Hung, LuSheng-Nan, ShenChien-Heng, TungShui-Yi, WeiKuo-Liang, YenChih-Wei

Paper Details 
Original Abstract of the Article :
The real-world data of glecaprevir/pibrentasvir (GLE/PIB) therapy for patients with chronic hepatitis C virus (HCV) genotype 2 infection remained limited. We aimed to evaluate the possible predictors of virological failure and side effects of GLE/PIB therapy for chronic genotype 2 HCV-infected patie...See full text at original site
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引用元:
https://doi.org/10.1016/j.jfma.2020.08.010

データ提供:米国国立医学図書館(NLM)

Predicting Virologic Failure in Hepatitis C Genotype 2: A Real-World Perspective

The desert of [hepatitis C virus] (HCV) infection can be a challenging and unpredictable landscape, with treatment outcomes varying widely. This study ventures into the real-world setting of [glecaprevir/pibrentasvir] (GLE/PIB) therapy for patients with chronic HCV genotype 2 infection, seeking to identify potential predictors of virologic failure. Researchers analyzed data from a real-world cohort of patients, exploring the relationship between various factors and treatment outcomes. They discovered that high viral load at baseline was a significant predictor of virologic failure, highlighting the importance of early detection and treatment for optimizing treatment outcomes.

The Importance of Early Detection and Treatment

This study underscores the crucial role of early detection and treatment in managing HCV infection. The findings suggest that individuals with high viral loads at baseline might require closer monitoring and tailored treatment strategies to increase the chances of achieving a sustained virologic response. Early intervention is key to navigating the desert of HCV infection effectively and minimizing the risk of long-term complications.

Navigating the HCV Desert: A Path Toward Recovery

HCV infection can be a significant health challenge, but with advancements in treatment options and a focus on early detection, there is hope for a brighter future. If you are at risk of HCV infection or have been diagnosed with HCV, it's important to consult with your healthcare provider to discuss appropriate testing, treatment options, and lifestyle modifications. Remember, seeking guidance and taking proactive steps can help you navigate the desert of HCV infection and work towards recovery.

Dr.Camel's Conclusion

This study highlights the importance of early detection and treatment in achieving sustained virologic response in HCV genotype 2 patients receiving GLE/PIB therapy. The study emphasizes the need for careful monitoring of viral load and tailored treatment strategies to improve treatment outcomes and guide patients towards a healthy future. It's a reminder that even in the face of challenging medical conditions, early action and ongoing care can lead to a successful journey through the desert of HCV infection.

Date :
  1. Date Completed 2021-02-16
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

32839045

DOI: Digital Object Identifier

10.1016/j.jfma.2020.08.010

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SNS
PICO Info
in preparation
Languages

English

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