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Life-threatening disseminated enterovirus infection during combined rituximab and ibrutinib maintenance treatment for mantle cell lymphoma: a case report.
Author: CanaDenis, HessGeorg, HigerMaximilian, PodlechJuergen, Schadmand-FischerSimin, SchwartingAndreas, TeschnerDaniel, TheobaldMatthias, WölfelThomas
Original Abstract of the Article :
Rituximab is a well-established component of treatment regimens for B-cell non-Hodgkin lymphoma. Rituximab binds the CD20 antigen on the surface of B lymphocytes, causing an enhanced clearance of malignant and benign B cells. Thus, rituximab leads to depletion of normal B lymphocytes as well, which ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456041/
データ提供:米国国立医学図書館(NLM)
A Case of Life-Threatening Enterovirus Infection: When Immune Suppression Meets Viral Invasion
The immune system is like a protective oasis in the desert of our bodies, shielding us from harmful invaders. However, when this oasis is compromised, we become vulnerable to infection. This study explores the complex interplay between immune suppression and viral infection, highlighting a case of life-threatening disseminated enterovirus infection in a patient undergoing combined rituximab and ibrutinib treatment for mantle cell lymphoma. These drugs, while effective in treating lymphoma, can significantly suppress the immune system, leaving the patient susceptible to opportunistic infections.
Navigating the Desert of Immune Suppression
This case study serves as a reminder that immune suppression, while a necessary part of some cancer treatments, can have serious consequences. Close monitoring and prompt intervention are crucial for managing the risks associated with immune suppression and preventing potentially life-threatening infections.
The Importance of Vigilance and Early Intervention
This case highlights the importance of vigilance and early intervention in patients undergoing immune-suppressive therapies. Regular monitoring for signs of infection and prompt treatment are vital for ensuring patient safety and minimizing the risks associated with immune suppression.
Dr. Camel's Conclusion
This case study underscores the delicate balance between fighting cancer and protecting the immune system. It reminds us that while immune suppression can be a powerful tool in cancer treatment, it's crucial to remain vigilant and address potential complications promptly. This case serves as a valuable lesson in navigating the desert of immune suppression, emphasizing the importance of careful monitoring and early intervention.
Date :
- Date Completed 2021-05-14
- Date Revised 2021-05-14
Further Info :
Related Literature
English
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