Pharmacogenomics of COVID-19 therapies.

Author: JacobsonPamala A, LuzumJasmine A, NicolMelanie R, TakahashiTakuto

Paper Details 
Original Abstract of the Article :
A new global pandemic of coronavirus disease 2019 (COVID-19) has resulted in high mortality and morbidity. Currently numerous drugs are under expedited investigations without well-established safety or efficacy data. Pharmacogenomics may allow individualization of these drugs thereby improving effic...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435176/

データ提供:米国国立医学図書館(NLM)

Pharmacogenomics of COVID-19 Therapies: Navigating the Genetic Desert

This research explores the exciting frontier of [Pharmacogenomics], focusing on the role of genetic variations in influencing the efficacy and safety of COVID-19 therapies. The study reviewed available pharmacogenomic literature for various COVID-19 drugs, including hydroxychloroquine, chloroquine, azithromycin, remdesivir, favipiravir, ribavirin, lopinavir/ritonavir, darunavir/cobicistat, interferon beta-1b, tocilizumab, ruxolitinib, baricitinib, and corticosteroids. The researchers identified several drug-gene variant pairs that could potentially alter the pharmacokinetics and adverse effects of these drugs, highlighting the importance of individualizing treatment based on genetic profiles. The findings suggest that pharmacogenomics could play a crucial role in optimizing COVID-19 treatment, improving efficacy and minimizing adverse reactions.

Genetic Variations: A Roadmap for Personalized Therapy

This research emphasizes the potential of pharmacogenomics to revolutionize COVID-19 treatment. It's like finding a detailed map in a vast desert, guiding us towards a more tailored and effective approach to therapy. These findings underscore the need for further research to validate and implement pharmacogenomic testing in clinical practice, enabling us to personalize treatments and optimize patient outcomes.

Navigating the COVID-19 Treatment Landscape: A Genetic Compass

This research serves as a reminder of the evolving landscape of COVID-19 treatment. It highlights the importance of staying abreast of new developments and incorporating pharmacogenomics into our clinical decision-making. Just as a desert traveler uses a compass to navigate the unknown, we must embrace personalized medicine to navigate the complexities of COVID-19 therapy, ensuring optimal patient care.

Dr.Camel's Conclusion

This research throws a spotlight on the burgeoning field of pharmacogenomics, showcasing its potential to transform COVID-19 treatment. The study reveals that genetic variations can significantly influence the efficacy and safety of COVID-19 therapies, emphasizing the need for personalized medicine to optimize patient outcomes. Just as a camel adapts its strategy to navigate the diverse terrain of the desert, we must adapt our approach to COVID-19 treatment, embracing the power of pharmacogenomics to ensure effective and safe therapeutic interventions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-07-17
Further Info :

Pubmed ID

32864162

DOI: Digital Object Identifier

PMC7435176

Related Literature

SNS
PICO Info
in preparation
Languages

English

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