Paper Details

  1. Home
  2. Paper Details

Comparative efficacy and safety of drug treatment for premature ejaculation: A systemic review and Bayesian network meta-analysis.

Author: CaiHongcai, DengChunhua, HuangMingchuan, LiuGuihua, LiuHanchao, ZhangMingxiao, ZhangYadong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

The study assessed the comparative efficacy and safety of drug treatments for premature ejaculation (PE) in 11,008 patients through a systematic review and Bayesian network meta-analysis of 44 randomized controlled trials. The drug combination of SSRI + PDE5i was the most effective PE therapy in ≥ 8 weeks of therapy, while local anesthetics were most effective in < 8 weeks of therapy. All drug treatments were ranked better than placebo, but drugs with better effects had more obvious side effects.
Paper Details　
Original Abstract of the Article :
To assess the comparative efficacy and safety of drug treatments for premature ejaculation. A systemic review and Bayesian network meta-analysis were executed on randomised controlled trials of drug interventions for premature ejaculation. Intravaginal ejaculation latency time and related adverse ef...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/and.13806

データ提供：米国国立医学図書館（NLM）

Treating Premature Ejaculation: A Comprehensive Look at Drug Options

Premature ejaculation (PE) is a common sexual dysfunction that can affect men's quality of life. This study, like a camel navigating a challenging desert landscape, explores the comparative efficacy and safety of various drug treatments for PE.

The researchers conducted a systematic review and Bayesian network meta-analysis of randomized controlled trials (RCTs) investigating drug interventions for PE. They compared the efficacy of different drug classes, including topical creams, selective serotonin reuptake inhibitors (SSRIs), phosphodiesterase 5 inhibitors (PDE5is), and others, in terms of intravaginal ejaculation latency time (IELT) and adverse effects.

The meta-analysis found that the combination of SSRIs and PDE5is was the most effective treatment for PE in therapy lasting ≥8 weeks. Topical creams were most effective in therapy <8 weeks. Overall, the study suggests that drug treatments for PE are generally more effective than placebo, but those with better effects tend to have more side effects.

A Comprehensive Guide to Drug Treatments for Premature Ejaculation

This study provides a comprehensive overview of the comparative efficacy and safety of various drug treatments for PE. The findings can guide healthcare providers in selecting the most appropriate treatment options for individual patients, considering their specific needs and risk factors.

Navigating the Challenges of Sexual Dysfunction

This study highlights the importance of understanding the different treatment options for PE and the need for careful consideration of the potential benefits and risks of each option. It emphasizes the importance of open communication between patients and healthcare providers to ensure effective management of this common sexual dysfunction.

Dr.Camel's Conclusion

This study offers valuable insights into the comparative efficacy and safety of drug treatments for premature ejaculation. The findings can help guide healthcare providers in selecting the most appropriate treatment options for their patients, considering the individual needs and risk factors.

Date :
  1. Date Completed 2021-05-24
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

32892379

DOI: Digital Object Identifier

10.1111/and.13806

Related Literature

Article Analysis
・Side Effects of citalopram
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.