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Prevalence and management of constipation in pediatric acute lymphoblastic leukemia in U.S. children's hospitals.

Author: BelskyJennifer A, O'BrienSarah H, StanekJoseph R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Constipation was the most common gastrointestinal diagnosis in hospitalized children with acute lymphoblastic leukemia (ALL), affecting 33.9% of patients during induction admission. Younger age (<6 years), female sex, longer hospital stay, and opioid use were significantly associated with constipation.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Children with acute lymphoblastic leukemia (ALL) suffer from a litany of chemotherapy-induced side effects. Constipation secondary to vinca alkaloids, environmental changes, and opioid use is a common issue for children newly diagnosed with leukemia. PROCEDURE: We analyzed data from 48 ...See full text at original site
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引用元：
https://doi.org/10.1002/pbc.28659

データ提供：米国国立医学図書館（NLM）

Constipation in Children with Acute Lymphoblastic Leukemia: A Common Challenge

Acute lymphoblastic leukemia (ALL) is a serious type of cancer that affects the blood and bone marrow. Chemotherapy, a common treatment for ALL, can have many side effects, including constipation. This study focused on the prevalence, risk factors, and management of constipation in children hospitalized with ALL. Imagine a young camel struggling to navigate a maze of winding sand dunes - this is the challenge that many children with ALL face, and constipation is one of the obstacles they must overcome.

Constipation in Children with ALL: A Closer Look at the Data

The researchers found that constipation was a common problem in children with ALL, affecting more than one-third of patients during their initial hospitalization. They also identified a number of risk factors for constipation, including younger age, female sex, longer hospital stays, and opioid use. The study also highlighted the use of various medications, particularly polyethylene glycol, to manage constipation.

Navigating the Desert of Side Effects

This research highlights the importance of proactive constipation prevention and management in children with ALL. It underscores the need for careful monitoring and timely intervention to minimize discomfort and improve quality of life during treatment. Like a skilled camel guide leading a caravan, doctors and nurses play a critical role in helping these children navigate the challenges of their treatment journey.

Dr.Camel's Conclusion

This study provides a clear picture of the prevalence and management of constipation in children with ALL. The findings emphasize the need for proactive strategies to prevent and treat this common side effect, improving the overall well-being of these young patients. Just as a wise camel prepares for a journey through the desert, healthcare providers must be prepared to address the unique needs of children with ALL, ensuring their comfort and recovery.

Date :
  1. Date Completed 2021-01-19
  2. Date Revised 2021-01-19
Further Info :

Pubmed ID

32893981

DOI: Digital Object Identifier

10.1002/pbc.28659

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Languages

English

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