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Analysis of musculoskeletal side effects of oral Isotretinoin treatment: a cross-sectional study.

Author: KaraosmanoğluNermin, MülkoğluCevriye

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A study was conducted to evaluate musculoskeletal side effects of systemic isotretinoin treatment in patients with acne vulgaris. The study found that low back pain is one of the very common complications of isotretinoin. It can be mostly mechanical or inflammatory. Isotretinoin-induced low back pain is dose-related. Clinicians should be aware that back pain may be a reflective of sacroiliitis during isotretinoin usage.
Paper Details　
Original Abstract of the Article :
BACKGROUND/ OBJECTIVES: Acne vulgaris is a chronic inflammatory disease affecting the pilosebaceous unit. Isotretinoin is an effective treatment option for severe acne. The aim of this study was to evaluate musculoskeletal side effects of systemic isotretinoin treatment. METHODS: Ninety-four patien...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519514/

データ提供：米国国立医学図書館（NLM）

Isotretinoin and Musculoskeletal Health: Navigating the Desert of Side Effects

Isotretinoin is a highly effective treatment for severe acne, but like many medications, it can come with side effects. This study explores the musculoskeletal side effects of isotretinoin, investigating the potential impact of this medication on joint and muscle health. It's like exploring the desert landscape, searching for hidden dangers and potential pitfalls along the way.

A Desert of Side Effects: Understanding the Risks

The researchers found that musculoskeletal side effects, particularly low back pain, were common among patients taking isotretinoin. While some cases were due to mechanical pain, others were associated with inflammation. This suggests that isotretinoin can potentially trigger inflammatory processes in the musculoskeletal system. It's like discovering a hidden oasis that is susceptible to unexpected droughts and storms.

Managing the Desert: Staying Vigilant for Side Effects

This study underscores the importance of careful monitoring for musculoskeletal side effects in patients taking isotretinoin. It’s like being aware of the potential hazards of the desert landscape and taking precautions to avoid them. By carefully assessing patients and addressing potential complications, healthcare professionals can help ensure a safe and effective treatment journey.

Dr.Camel's Conclusion

This study reminds us that even powerful medications, like those used to treat severe acne, can have unintended consequences. It's like finding a hidden oasis in the desert, but realizing that it can also be affected by unexpected storms. By understanding the potential risks and managing them carefully, we can help ensure a safer and more effective treatment journey for patients.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

32977793

DOI: Digital Object Identifier

PMC7519514

Related Literature

Article Analysis
・Side Effects of isotretinoin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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