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TAS-102 in metastatic colorectal cancer (mCRC): efficacy, tolerability, and quality of life in heavily pretreated elderly patients: a real-life study.

Author: AddeoRaffaele, CiceroGiuseppe, De LucaRossella, GulottaGaspare, GulottaLeonardo, Lo ReGiuseppe, MarchesaPierenrico

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

TAS-102, a combination of trifluridine and tipiracil hydrochloride, is an effective treatment for patients with metastatic colorectal cancer whose disease has progressed with standard therapies. This drug has been shown to be effective and safe in elderly patients who have received several prior treatments.
Paper Details　
Original Abstract of the Article :
TAS-102 is an oral monotherapy, combining trifluridine and tipiracil hydrochloride, indicated for the treatment of pretreated metastatic colorectal cancer (mCRC). The aim of this real-life study is to evaluate the efficacy and safety of TAS-102 in heavily pretreated elderly patients with mCRC whose ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505119/

データ提供：米国国立医学図書館（NLM）

TAS-102: A Promising Treatment for Metastatic Colorectal Cancer

In the ongoing battle against metastatic colorectal cancer (mCRC), the search for effective treatments is a top priority. This real-life study explores the efficacy and safety of TAS-102, an oral monotherapy combining trifluridine and tipiracil hydrochloride, in heavily pretreated elderly patients with mCRC. The study aims to assess the effectiveness of TAS-102 in patients whose disease has progressed despite standard therapies.

TAS-102 Shows Promise: Efficacy and Tolerability in Elderly Patients

The study provides valuable insights into the potential of TAS-102 for treating mCRC in elderly patients. The results suggest that TAS-102 can be an effective treatment option for these individuals, offering hope in challenging clinical scenarios. The study also emphasizes the tolerability of TAS-102, a key consideration for elderly patients who may be more vulnerable to side effects.

A Glimpse of Hope for Cancer Patients: Balancing Efficacy and Safety

The study highlights the crucial importance of finding treatments that are both effective and well-tolerated, especially for elderly patients with mCRC. TAS-102 appears to strike a balance between efficacy and safety, offering a potential lifeline for patients who have exhausted other options. This is like discovering a hidden spring in the desert – a source of hope and relief for those seeking a path to recovery.

Dr. Camel's Conclusion

TAS-102 shows promise as a treatment option for heavily pretreated elderly patients with metastatic colorectal cancer. This study provides valuable insights into the efficacy and tolerability of TAS-102, offering a potential pathway for improving patient outcomes in this challenging disease. Further research is needed to solidify these findings and explore the long-term benefits of TAS-102. In the vast desert of cancer research, TAS-102 emerges as a beacon of hope, illuminating a possible path towards better treatment options for patients with mCRC.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-17
Further Info :

Pubmed ID

32994802

DOI: Digital Object Identifier

PMC7505119

Related Literature

Article Analysis
・Side Effects of trifluridine and tipiracil
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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