Protective effects of taxifolin on pazopanib-induced liver toxicity: an experimental rat model.

Author: AkagunduzBaran, KaraAli Veysel, LacınSahin, MammadovRenad, OzcıcekFatih, OzerMuhammet, SuleymanBahadır, SuleymanHalis, ÇobanAbdulkadir, ÖzkaracaMustafa

Paper Details 
Original Abstract of the Article :
Pazopanib is a tyrosine kinase inhibitor that is generally used for the treatment of metastatic renal cell cancer and advanced soft tissue sarcoma. It can cause various degrees of hepatotoxicity. Our study aimed to investigate the effect of taxifolin on pazopanib-induced liver toxicity. A total of 1...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150244/

データ提供:米国国立医学図書館(NLM)

Protecting the Liver: A New Approach to Cancer Treatment

Pazopanib, a powerful weapon in the fight against cancer, can sometimes have unintended consequences, leading to liver toxicity. This study explores the potential of taxifolin, a natural compound, to mitigate this risk. The study utilizes an experimental rat model to investigate the protective effects of taxifolin against pazopanib-induced liver toxicity. The results of this study could have significant implications for the development of safer and more effective cancer treatments.

Unveiling the Protective Powers of Taxifolin: A Light at the End of the Tunnel

The study found that taxifolin significantly reduced the liver damage caused by pazopanib, offering a potential solution to a critical side effect of this important cancer drug. This discovery holds immense promise for improving the safety and efficacy of cancer treatments, potentially reducing the risk of liver complications for patients.

Safer Cancer Treatment: A Glimpse into the Future

This study provides a glimmer of hope for safer cancer treatments, suggesting that natural compounds like taxifolin could play a crucial role in mitigating the side effects of powerful cancer drugs. This research underscores the importance of exploring natural remedies in conjunction with conventional treatments, paving the way for more effective and less toxic therapies.

Dr.Camel's Conclusion

This study sheds light on the potential of taxifolin to mitigate the liver toxicity associated with pazopanib, offering a glimmer of hope for safer and more effective cancer treatments. It emphasizes the importance of exploring natural compounds to enhance the safety and efficacy of cancer therapies, leading towards a future where patients can benefit from powerful cancer treatments without compromising their health.

Date :
  1. Date Completed 2021-09-08
  2. Date Revised 2021-09-08
Further Info :

Pubmed ID

33239495

DOI: Digital Object Identifier

PMC8150244

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English

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