Successful use of golimumab in a patient with ulcerative colitis refractory to infliximab and adalimumab.

Author: AntequeraBeatríz, Borrás-BlascoJoaquín, CasteráElvira, CortesXavier, Fernandez-MartinezSergio, FlorLaura, MolésJose Ramón

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To report a case of successful use of golimumab (GLB) in a patient with ulcerative colitis (UC) refractory to infliximab (IFX) and adalimumab (ADA). CASE SUMMARY: A 60-year-old man was diagnosed with left UC and was given azathioprine 2.5 mg/kg to control UC symptoms and decrease cortico...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.5414/CP202621

データ提供:米国国立医学図書館(NLM)

Golimumab: A Potential Rescue Treatment for Ulcerative Colitis Refractory to Infliximab and Adalimumab

This case report, like a skilled physician seeking a solution for a complex medical challenge, describes the successful use of [golimumab (GLB)] in a patient with [ulcerative colitis (UC)] refractory to conventional treatments. The patient, having experienced a severe UC relapse and failed responses to infliximab (IFX) and adalimumab (ADA), faced a daunting medical journey. This report, much like a desert guide leading a traveler through unfamiliar terrain, offers a potential alternative treatment strategy for patients with refractory UC.

Golimumab: A Potential Alternative for Refractory Ulcerative Colitis

The case report demonstrates that [golimumab] can be an effective treatment option for patients with [ulcerative colitis] that has not responded to conventional therapies. This finding, like a hidden oasis providing a respite from the harsh desert conditions, offers hope for patients with refractory UC who have exhausted other treatment options.

Implications for Ulcerative Colitis Management

This case report, while limited in scope, highlights the potential of [golimumab] as a rescue treatment for patients with refractory UC. Further research is needed to confirm its efficacy in larger patient populations, but this initial observation suggests a promising avenue for improving outcomes for individuals struggling with this challenging condition.

Dr.Camel's Conclusion

This case report, like a camel finding a hidden oasis in the vast desert, provides a glimmer of hope for patients with ulcerative colitis who have not responded to conventional treatments. The successful use of golimumab in this case highlights the importance of exploring new treatment strategies for refractory UC, paving the way for better outcomes for those affected by this debilitating condition.

Date :
  1. Date Completed 2021-04-14
  2. Date Revised 2021-04-14
Further Info :

Pubmed ID

33261721

DOI: Digital Object Identifier

10.5414/CP202621

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.