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Primaquine overdose in a toddler.
Author: PomeranzElaine, PonceDaphne Morrison, SchaefferWilliam, ViscloskyTimothy
Original Abstract of the Article :
Antimalarial medications carry a risk of rare, but serious side effects. Primaquine in particular is known to cause methemoglobinemia and hemolytic anemia. In patients with underlying glucose-6-phosphate dehydrogenase (G6PD) deficiency, these side effects become amplified and can be life-threatening...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.ajem.2020.10.084
データ提供:米国国立医学図書館(NLM)
Primaquine Overdose in a Toddler: A Case of Methemoglobinemia and Hemolytic Anemia
This case report describes a rare and potentially life-threatening situation involving a toddler who accidentally overdosed on primaquine, an antimalarial medication. It's like a desert mirage, revealing a hidden danger in the seemingly safe world of medication. The researchers present a unique case of a patient with undiagnosed glucose-6-phosphate dehydrogenase (G6PD) deficiency who experienced severe methemoglobinemia and hemolytic anemia after primaquine overdose.
Primaquine Overdose: A Potential for Severe Complications
This case report highlights the potential for serious complications, including methemoglobinemia and hemolytic anemia, following primaquine overdose, especially in individuals with G6PD deficiency. It's like a hidden trap in the desert, revealing the importance of careful monitoring and appropriate management of drug-related complications. The case underscores the need for a high index of suspicion and prompt intervention to prevent life-threatening consequences.
Managing Primaquine Overdose: A Complex Challenge
This case demonstrates the complexities of managing primaquine overdose, particularly in patients with G6PD deficiency. It's like navigating a sandstorm in the desert, requiring quick thinking and careful decision-making to address the unique challenges of this situation. The case emphasizes the need for a multidisciplinary approach involving pediatricians, pharmacists, and other healthcare professionals to ensure effective patient care.
Dr.Camel's Conclusion
This case report serves as a reminder that even seemingly safe medications can pose significant risks, especially in vulnerable populations like children. It's a call to action for healthcare professionals to be vigilant in monitoring patients, understanding drug interactions, and responding quickly to potential complications. By embracing a proactive approach to patient care, we can minimize the risk of adverse drug events and ensure the safety of our patients.
Date :
- Date Completed 2021-08-25
- Date Revised 2021-08-25
Further Info :
Related Literature
English
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